Project description:We report the application of single-molecule-based sequencing technology for high-throughput profiling of DNA methylations in Burkholderia pseudomallei.

2014-09-15 | GSE55168 | GEO

Methylome sequencing of Burkholderia pseudomallei D286, H10, PMC2000, R15 and 982

Project description:We report the methylome sequencing and annotation of Burkholderia pseudomallei D286 based on high-throughput profiling using PacBio SMRT technology

2019-09-25 | GSE137930 | GEO

Role of ppiB in burkholderia pseudomallei

Project description:Burkholderia pseudomallei is the causative agent of melioidosis a disease endemic in South-East Asia and Northern Australia. The mortality rates in these areas are unacceptably high even with antibiotic treatment, attributed to intrinsic and acquired resistance of B. pseudomallei to antibiotics. With very few options for therapeutics there is an urgent requirement to identify anti-bacterial targets for the development of novel, effective treatments. In this study we examine the role and effect of ppiB on the proteome. Using LFQ analysis we show loss of ppiB has dramatic effect on the Burkholderia pseudomallei proteome.

2019-08-05 | PXD012956 | Pride

Genomic Loss of Penicillin-Binding Protein 3 in Burkholderia pseudomallei Confers Clinical Resistance to Ceftazidime

Project description:Array-CGH analysis and Burkholderia pseudomallei isolates pre and post ceftazidime relapse.

2011-10-07 | GSE25832 | GEO

Toxicogenomic Effect of Burkholderia pseudomallei in a Human Macrophage Cell (THP-1) Model of Acute Melioidosis Using Whole-genome Microarray

Project description:Gene expression profiles of human cell (THP-1) lines exposed to a novel Daboiatoxin (DbTx) isolated from Daboia russelli russelli, and specific cytokines and inflammatory pathways involved in acute infection caused by Burkholderia pseudomallei. Keywords: Melioidosis, Burkholderia pseudomallei, Daboiatoxin, Cytokines, Inflammation.

2010-05-31 | GSE7577 | GEO

Burkholderia pseudomallei strain:VB976100 | isolate:VB976100 | breed:Burkholderia pseudomallei

Project description:Burkholderia pseudomallei strain:VB976100 | isolate:VB976100 | breed:Burkholderia pseudomallei Genome sequencing

| PRJNA349440 | ENA