Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Mitochondrial genomes of animals

PROVIDER: PRJNA1033669 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26586302_1.fastq.gz	Fastqsanger.gz
	SRR26586302_2.fastq.gz	Fastqsanger.gz
	SRR28492289_1.fastq.gz	Fastqsanger.gz
	SRR28492289_2.fastq.gz	Fastqsanger.gz
	SRR28492290_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 76

Similar Datasets

Project description:The study of complete mitochondrial genomes of marine animals

| PRJNA753924 | ENA

TFAM ChIP-seq in HeLa cells

Project description:ChIP-seq data characterizing the occupancy of TFAM over the mitochondrial and nuclear genomes in HeLa cells. Characterization of mitochondrial and nuclear genome-wide TFAM binding in HeLa cells

2013-09-21 | E-GEOD-48176 | biostudies-arrayexpress

The strand-biased mitochondrial DNA methylome and its regulation by DNMT3A [HEK293T_MeDIP]

Project description:How individual genes are regulated from a mitochondrial polycistronic transcript to have variable expression remains an enigma. Here, through bisulfite sequencing and strand-specific mapping, we show mitochondrial genomes in human and other animals were strongly biased to light (L)-strand non-CpG methylation with conserved peak loci preferentially located at gene-gene boundaries, which was also independently validated by MeDIP and FspEI digestion. Such mtDNA methylation patterns are conserved across different species and developmental stages, but display dynamic local or global changes during development and aging. Knockout of DNMT3A alone perturbed mtDNA regional methylation patterns, but not global levels, and altered mitochondrial gene expression, copy number, and oxygen respiration. Overexpression of DNMT3A strongly increased mtDNA methylation and strand bias. Overall, methylation at gene body and boundaries was negatively associated with mitochondrial transcript abundance and also polycistronic transcript processing. Furthermore, HPLC-MS confirmed the methylation signals on mitochondria DNA. Together, these data provide high-resolution mtDNA methylation maps that revealed a strand specific non-CpG methylation, its dynamic regulation and its impact on the polycistronic mitochondrial transcript processing. Through bisulfite sequencing and strand-specific mapping, we show mitochondrial genomes in human and other animals were strongly biased to light (L)-strand non-CpG methylation with conserved peak loci preferentially located at gene-gene boundaries, which was also independently validated by MeDIP and FspEI digestion.

2019-08-22 | GSE133958 | GEO

Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Polyneoptera Orthoptera Ensifera Gryllidea

Project description:Cricket mitochondrial genomes

| PRJNA739105 | ENA

Project description:1000 Mitochondrial Genomes

| PRJNA811355 | ENA

Project description:Mitochondrial genomes Rhabdocoela

| PRJNA606139 | ENA

Project description:insect mitochondrial genomes

| PRJNA758734 | ENA

Project description:Helianthus mitochondrial genomes

| PRJNA731105 | ENA