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MiRNA profiling of lung epithelial cells (BEAS-2B cells) exposed to manganese (Mn)

ABSTRACT: miRNA profiling of lung epithelial cells (BEAS-2B cells) exposed to manganese (Mn)

PROVIDER: PRJNA1034564 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR26628126_1.fastq.gz	Fastqsanger.gz
	SRR26628126_2.fastq.gz	Fastqsanger.gz
	SRR26628127_1.fastq.gz	Fastqsanger.gz
	SRR26628127_2.fastq.gz	Fastqsanger.gz

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miRNA profiling of lung epithelial cells (BEAS-2B cells) exposed to manganese (Mn)

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high-throughput sequencing of circRNAs in T-BEAS-2B cells and C-BEAS-2B cells

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HmiOA4.1 microarrays-BEAS-2B cells treatment with NiCl2

Project description:To investigate the effects of nickel on miRNAs expression in BEAS-2B cells.

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Expression data from BEAS-2B cells

Project description:BEAS-2B cells are human bronchial epithelial cells, and often used as a in vitro model for the detection of potential pulmonary toxicity of chemicals. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes after treated with chemical substance

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high-throughput sequencing of circRNAs in T-BEAS-2B cells and C-BEAS-2B cells

Project description:high-throughput sequencing of circRNAs in T-BEAS-2B cells and C-BEAS-2B cells

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Expression data from BEAS-2B cells II

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Comparison of gene expression profiles in chromate transformed BEAS-2B cells

Project description:We established chromate transformed cell lines by chronic exposure of normal human bronchial epithelial BEAS-2B cells to low doses of hexavalent chromium followed by anchorage-independent growth. The gene expression profiles were analyzed in the established cell lines. The gene expression profiles from six chromate transformed cell lines were remarkably similar to each other yet differed significantly from that of either control cell line or normal Beas-2B cells. A total of 409 differentially expressed genes were identified in chromate transformed cells compared to control cells. We analyzed gene expression profiles from 10 cell lines ( six chromated transformed cells lines, three control cell lines, and parental BEAS-2B cells) using Affymetrix Human Gene 1.0 ST array. No techinical replicates were performed.

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