Project description:We investigate the global miRNA expression profile of An. sinensis using illumine Hiseq 2000 sequencing.The annotation and prediction of miRNAs lays the foundation for the further functional study of An. sinensis miRNAs and will facilitate their application in vector control.

2018-09-27 | GSE109005 | GEO

Amblyomma maculatum isolate:Adult female

Project description:Amblyomma maculatum isolate:Adult female Genome sequencing

| PRJNA933187 | ENA

Ochlerotatus sierrensis isolate:single adult female

Project description:Ochlerotatus sierrensis isolate:single adult female Genome sequencing

| PRJNA1119052 | ENA

Tenodera angustipennis

Project description:Tenodera angustipennis overview

| PRJNA873842 | ENA

Anopheles sinensis

Project description:Anopheles sinensis adult female sialotranscriptome

| PRJNA321832 | ENA

Human cholangiocarcinoma cells treated with Clonorchis sinensis excretory-secretory products.

Project description:Clonorchiasis is associated with bile duct malignancy and the subsequent development of cholangiocarcinoma. Although this is likely caused by adult Clonorchis sinensis and its excretory-secretory products (ESP), the precise molecular mechanisms remain obscure. To evaluate the effect of C. sinensis infection on differential gene expression in host hepatocytes, we used cDNA microarrays in human cholangiocarcinoma cells through the mimicking of C. sinensis infestation, and analyzed differential mRNA expression patterns of host cells. Keywords: Time course

2008-07-24 | GSE12213 | GEO

Transcriptome-wide N6-Methyladenosine (m6A) modifications in Anopheles sinensis

Project description:We profile transcriptome-wide m6A in female and male Anopheles sinensis and reveal that m6A is also a highly conserved modification of mRNA in mosquitoes were generated by deep sequencing, in triplicate, using illumina Novaseq™ 6000. Distinct from mammals and yeast, but similar to Arabidopsis thaliana, m6A in An. sinensis is enriched not only around the stop codon and within 3’-untranslated regions, but also around the start codon and 5’-UTR. Gene ontology analysis indicates that the unique distribution pattern of m6A in An. sinensis is associated with mosquito sex-specific pathways. In addition, the positive correlation between m6A deposition and mRNA abundance indicates that m6A can play roles in regulating gene expression in mosquitoes. Our study proposed a transcriptional regulatory network of m6A in An. sinensis, which may provide a new clue for the control of this disease-transmitting vector.

2022-05-18 | GSE193379 | GEO

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