Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Characterisation of ILCs isolated from Mtb infected mice lungs

ABSTRACT: Characterisation of ILCs isolated from Mtb infected mice lungs

PROVIDER: PRJNA1050155 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR27144260.fastq.gz	Fastqsanger.gz
	SRR27144261.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Characterisation of ILCs isolated from Mtb infected mice lungs

Project description:ILCs were sorted from the lungs of Mtb infected mice at 5 and 14 days post infection and subjected to sc-RNA sequencing to determine gene signature profile

2024-02-15 | GSE249667 | GEO

Effect of PDE4 inhibition on host gene expression of Mtb-infected mouse lungs.

Project description:Global gene expressions of Mtb-infected mouse lungs were compared between with and without PDE4 inhibitor treatment. A lot of host genes are differentially expressed 21d and 28d post-Mtb infection. PDE4 inhibitor, however, downregulate 10% of genes among those and genes differentially regulated by PDE4 inhibitor are mainly involved immune response. Total RNA was isolated from Mtb-infected mouse lungs with or without CC-3052 (25 mg/kg/day) using Trizol reagent and gene profile was analyed using Affymetrix mouse ST 1.0

2010-11-13 | E-GEOD-25313 | biostudies-arrayexpress

Characterization of CD4 T cells isolated from Mtb-infected lungs

Project description:Characterization of CD4 T cells isolated from Mtb-infected lungs

| PRJNA695219 | ENA

Effect of PDE4 inhibition on host gene expression of Mtb-infected mouse lungs.

2010-11-13 | GSE25313 | GEO

Characterization of CD4 T cells isolated from Mtb-infected lungs

Project description:CD4+ T cells were sorted from the lungs of differentially treated mice and subjected to RNA sequencing to determine global gene signature profile

2021-09-14 | GSE165614 | GEO

RNAseq of rabbit lungs infected with Mycobacterium tuberculosis as single cells or aggregates

Project description:The virulence of Mycobacterium tuberculosis (Mtb), either as mostly aggregates or single cells (Mtb-SC), was compared using a rabbit model of pulmonary infection. Our hypothesis is that aggregation contributes to enhanced virulence of Mtb. Rabbit lung transcriptome was analyzed by RNAseq to identify differentially regulated gene networks and pathways between Mtb-AG and Mtb-SC infection of rabbit lungs soon after seeding of the bacteria (24 hours post-inoculation).

2021-09-22 | GSE176139 | GEO

GeoMX WGS of Mtb-infected mouse lesions

Project description:To gain holistic of the immune landscape of lesions following infection with Mycobacterium tuberculosis, we aerosol infected C3HeB/FeJ mice with 1-3 CFU of Mtb (SA161 strain). 35 days following infection, lungs were harvested and fixed, then embedded and frozed in OCT. 10um sections were obtained, classified as necrotic or non-necrotic by visual inspection and brightfield imaging, then stained with markers delineating lesions, and subsequently processed and sampled using the nanostring GeoMX platform. We then compared the transcriptional environment of necrotic vs non-necrotic lesions

2024-04-17 | GSE264267 | GEO

Secretome of Mtb infected cells

Project description:Supplementary data of secretome of Mtb infected cells.

2020-01-30 | MSV000084863 | MassIVE

Gene expression analysis in lungs of Mtb infected Fth+/+ and Fth-/- mice by employing RNA-Seq

Project description:Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study is to compare gene expression (RNA-seq) profile between Mtb infected Fth+/+ and Fth-/- mice at 9 weeks post Mtb infection. Gene expression analysis demonstrated an essential role for FtH in mitochondrial function and maintenance of central intermediary metabolism in vivo

2018-09-01 | GSE112361 | GEO

Bulk RNA seq of sorted CD11c cells from lungs of uninfected and Mtb infected wild type mice.

Project description:To understand the difference between CD11c population from the uninfected and MTB HN878 infected mice at transcriptome level.

2024-07-05 | GSE249963 | GEO