The effects of HSP60 chaperone deficiency on zebrafish larvae
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ABSTRACT:
PROVIDER: PRJNA1068542 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR27715729_1.fastq.gz | Fastqsanger.gz | |||
| SRR27715729_2.fastq.gz | Fastqsanger.gz | |||
| SRR27715730_1.fastq.gz | Fastqsanger.gz | |||
| SRR27715730_2.fastq.gz | Fastqsanger.gz | |||
| SRR27715731_1.fastq.gz | Fastqsanger.gz |
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Project description:To understand the effects of Hsp60 deficiency in developing vertebrates, we generated CRISPR/Cas9-mediated hspd1 knockout zebrafish lines by targeting exon 2 to induce a frameshift mutation. We selected an allele with a 56 base pair deletion inducing a frameshift mutation leading to loss of protein functions. We examined the transcriptome changes in zebrafish larvae at 5 dpf .
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