Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cyanobacterial sigma factor controls biofilm-promoting genes through intra- and intercellular pathways

ABSTRACT: Cyanobacterial sigma factor controls biofilm-promoting genes through intra- and intercellular pathways

PROVIDER: PRJNA1069991 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR27751600.fastq.gz	Fastqsanger.gz
	SRR27751601.fastq.gz	Fastqsanger.gz
	SRR27751602.fastq.gz	Fastqsanger.gz
	SRR27751603.fastq.gz	Fastqsanger.gz
	SRR27751604.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 32

Similar Datasets

Cyanobacterial sigma factor controls biofilm-promoting genes through intra- and intercellular pathways

Project description:Cyanobacteria frequently constitute integral components of microbial communities known as phototrophic biofilms, which are widespread in various environments and hold significant industrial relevance. Previous studies of the model cyanobacterium Synechococcus elongatus PCC 7942 revealed that its planktonic growth habit results from a biofilm-suppression mechanism that depends on an extracellular inhibitor, an observation that opens the door to investigating cyanobacterial intercellular communication. Here, we demonstrate that the RNA polymerase sigma factor SigF1, is required for this biofilm-suppression mechanism and suggest that sigF1-inactivation impairs secretion of the biofilm inhibitor. The S. elongatus paralog SigF2, however, is not involved in biofilm regulation. Comprehensive transcriptome analyses identified distinct regulons under the control of each of these sigma factors. Additional data indicate that SigF1 regulates biofilm through its involvement in transcriptional induction of genes that include those for the primary pilus subunit: sigF1 inactivation both prevents pilus assembly and abrogates secretion of the biofilm inhibitor. Consequently, expression is significantly upregulated for the ebfG-operon that encodes matrix components and the genes that encode the corresponding secretion system. Thus, this study uncovers a basic regulatory component of cyanobacterial intercellular communication, a field that is in its infancy. Elevated expression of biofilm-promoting genes in a sigF1 mutant supports an additional layer of regulation by SigF1 that operates via an intracellular mechanism.

2024-09-13 | GSE254350 | GEO

Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism

Project description:Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism

| PRJNA1137857 | ENA

Cyanobacterial

Project description:Metatranscriptome of cyanobacterial aggregates

| PRJNA359157 | ENA

Cyanobacterial bloom

Project description:Cyanobacterial bloom Other

| PRJNA657047 | ENA

Sigma virus

Project description:sigma virus DMelSV raw sequence reads

| PRJNA326864 | ENA

Cyanobacterial biofilms

Project description:Cyanobacterial biofilm Raw sequence reads

| PRJNA975129 | ENA

Cyanobacterial Aggregate

Project description:Cyanobacterial Aggregate Metagenome Raw Sequence

| PRJNA664872 | ENA

Cyanobacterial Aggregates

Project description:Cyanobacterial Aggregates 16S rRNA Sequence

| PRJNA429935 | ENA

Springbrook cyanobacterial isolates

Project description:Springbrook cyanobacterial metagenomes

| PRJNA1030320 | ENA

A high resolution map of a cyanobacterial transcriptome

Project description:Previous molecular and mechanistic studies have identified several principles of prokaryotic transcription, but less is known about the global transcriptional architecture of bacterial genomes. Here we perform a comprehensive study of a cyanobacterial transcriptome, that of Synechococcus elongatus PCC 7942, generated by combining three high-resolution data sets: RNA sequencing, tiling expression microarrays, and RNA polymerase chromatin immunoprecipitation (ChIP) sequencing. We report absolute transcript levels, operon identification, and high-resolution mapping of 5' and 3' ends of transcripts. We identify several interesting features at promoters, within transcripts and in terminators relating to transcription initiation, elongation, and termination. Furthermore, we identify many putative non-coding transcripts. We provide a global analysis of a cyanobacterial transcriptome. Our results uncover insights that reinforce and extend the current views of bacterial transcription. RNA Sequencing of the cyanobacterium Synechococcus elongatus PCC 7942 RNA polymerase ChIP Sequencing of the cyanobacterium Synechococcus elongatus PCC 7942 Tiling Microarray of the cyanobacterium Synechococcus elongatus PCC 7942

2011-05-16 | E-GEOD-29264 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data