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Differential expression between WT and AhRR fetal liver macrophages

ABSTRACT: Differential expression between WT and AhRR fetal liver macrophages

PROVIDER: PRJNA1070258 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR27754121.fastq.gz	Fastqsanger.gz
	SRR27754122.fastq.gz	Fastqsanger.gz
	SRR27754123.fastq.gz	Fastqsanger.gz
	SRR27754124.fastq.gz	Fastqsanger.gz
	SRR27754125.fastq.gz	Fastqsanger.gz

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Differential expression between WT and AhRR fetal liver macrophages

Project description:We analyzed the gene expression differences in RNA-seq data of murine WT and AhRR fetal liver macrophages. RNA of 6 samples isolated and cultured for 5 weeks in vitro using GM-CSF.

2024-06-04 | GSE254369 | GEO

WT vs c-Maf KO fetal liver macrophage

Project description:Homozygous disruption of c-Maf led to embryonic lethality and impaired erythroblastic island formation. c-Maf is expressed in the fetal liver macrophages. It suggests that macrophages are responsible for the lethality of c-Maf knock-out embryos. To search downstream genes of c-Maf, we surveyed genes associated with macrophage function by microarray analysis. keywords: c-Maf, macrophage, erythroblastic islands, WT (c-Maf WT) and c-Maf KO (c-Maf KO) fetal liver macrophages were sorted by a FACSAria cell sorter. Total RNAs from those macrophages were prepared using RNeasy Kit. Genes down-regulated in c-Maf KO macrophages were searched by GeneSpring software.

2011-07-06 | E-GEOD-23305 | biostudies-arrayexpress

Differential gene expression in WT versus Hem1 KO macrophages

Project description:Differential gene expression in WT versus Hem1 KO macrophages

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Microarray expression level comparison between WT and KO fetal liver cells

Project description:Microarray expression level comparison between WT and KO fetal liver cells

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Hematopoiesis in Murine Fancd2-/- vs WT Fetal Liver

Project description:Hematopoiesis in Murine Fancd2-/- vs WT Fetal Liver

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ChIP-Chip data from WT E14.5 fetal liver

Project description:ChIP-Chip data from WT E14.5 fetal liver

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Hypoxia-induced translational profiles of murine fetal liver derived macrophages (FLDM)

Project description:We report changes in total and translated poly(A) RNA in mouse fetal liver derived macrophages after exposure to hypoxia. We employed translating ribosome affinity purification (TRAP) to isolate polysomal RNA from mouse fetal liver derived macrophages after exposure to hypoxia.

2023-09-07 | GSE196966 | GEO

WT vs c-Maf KO fetal liver macrophage

2011-07-06 | GSE23305 | GEO

Differential gene expression in WT versus Hem1 KO macrophages

Project description:Gene profiling, using microarray technology, was used to identify differentially expressed genes in bone marrow-differentiated macrophages of Hem1 KO versus Hem1 WT mice

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Capacity of yolk sac macrophages, fetal liver and adult monocytes to colonize an empty niche and develop into functional tissue resident macrophages

Project description:Tissue-resident macrophages can derive from yolk sac macrophages, fetal liver monocytes or adult bone marrow monocytes. Whether these precursors can give rise to transcriptionally identical alveolar macrophages is unknown. Here, we transferred traceable yolk sac macrophages, fetal liver monocytes, adult bone marrow monocytes or adult alveolar macrophages as a control, into the empty alveolar macrophage niche of neonatal Csf2rb-/- mice. All precursors efficiently colonized the alveolar niche and generated alveolar macrophages that were transcriptionally almost identical, with only 22 genes that could be linked to their origin. Underlining the physiological relevance of our findings, all transfer-derived alveolar macrophages self-maintained within the lungs for up to 1 year and durably prevented alveolar proteinosis. Thus, precursor origin does not affect the development of functional self-maintaining tissue-resident macrophages. CD45.1+CD45.2+ yolk sac macrophages, fetal liver monocytes, adult bone marrow monocytes or adult alveolar macrophages from the bronchoalveolar lavage were sorted from wild type CD45.1+CD45.2+ mice of indicated ages. From part of these samples RNA was isolated. The other part was transferred intranasally into the lungs of neonate Csf2rb-/- mice. 6 weeks post-transfer, transfer-derived CD45.1+CD45.2+ alveolar macrophages were sorted from the bronchoalveolar lavage. Wild type CD45.1+CD45.2 alveolar macrophages from the bronchoalveolar lavage of 6 week old mice were sorted as control. 36 samples (arrays) in total. RNA was isolated, amplified with Nugene pico kit, converted to cDNA and then hybridised on Affymetrix GeneChip Mouse Gene 1.0 ST Arrays.

2016-03-01 | E-GEOD-76999 | biostudies-arrayexpress

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