Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The neuronal architecture of autonomic dysreflexia

ABSTRACT: The neuronal architecture of autonomic dysreflexia

PROVIDER: PRJNA1079390 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28059227_1.fastq.gz	Fastqsanger.gz
	SRR28059227_2.fastq.gz	Fastqsanger.gz
	SRR28059228_1.fastq.gz	Fastqsanger.gz
	SRR28059228_2.fastq.gz	Fastqsanger.gz
	SRR28059229_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 26

Similar Datasets

The neuronal architecture of autonomic dysreflexia

Project description:This submission is a dataset of single-nucleus transcriptomics in the spinal cords of mice. The single-nuclei transcriptomics data is harvested and profiled using 10x Genomics Chromium Single Cell Kit Version.

2025-02-21 | GSE256423 | GEO

Robust regulatory architecture of pan-neuronal gene expression

Project description:Robust regulatory architecture of pan-neuronal gene expression

| PRJNA779059 | ENA

Expression data from rat regenerating livers after autonomic nervous system is disrupted

Project description:Autonomic nervous system is widely distributed in liver, and some reserchers have found that disruppted autonomic nerves will delay liver regeneration. We used microarrays to further highlight the regulatory role of autonomic nervous system in liver regeneration at gene transcription level. Surgical operations of rat partial hepatectomy (PH) and its operation control (OC), sympathectomy combining partial hepatectomy (SPH), vagotomy combining partial hepatectomy (VPH), and total liver denervation combining partial hepatectomy (TDPH) were performed, and the expression profiles of regenerating liver at 2h were detected using Rat Genome 230 2.0 array. Then the significantly changed genes related to liver regeneration (LR)-, injury-, splanchnic nerve-LR-, vagal nerve-LR-, and autonomic nerve-LR-related genes were identified, respectively. The relevance of gene expression profiles and biological processes was analyzed by bioinformatics and systems biology.

2010-12-18 | E-GEOD-26138 | biostudies-arrayexpress

Expression data from rat regenerating livers after autonomic nervous system is disrupted

2010-12-18 | GSE26138 | GEO

Chromatin architecture reorganisation during neuronal cell differentiation in Drosophila genome

Project description:Chromatin architecture reorganisation during neuronal cell differentiation in Drosophila genome

| PRJNA505701 | ENA

A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange

Project description:Alveolar formation increases the surface area for gas exchange. A molecular understanding of alveologenesis remains incomplete. Here, we show that the autonomic nerve and alveolar myofibroblast form a functional unit in mice. Myofibroblasts secrete neurotrophins to promote neurite extension/survival, whereas neurotransmitters released from autonomic terminals are necessary for myofibroblast proliferation and migration, a key step in alveologenesis. This establishes a functional link between autonomic innervation and alveolar formation. We also discover that planar cell polarity (PCP) signaling employs a Wnt-Fz/Ror-Vangl cascade to regulate the cytoskeleton and neurotransmitter trafficking/release from the terminals of autonomic nerves. This represents a new aspect of PCP signaling in conferring cellular properties. Together, these studies offer molecular insight into how autonomic activity controls alveolar formation. Our work also illustrates the fundamental principle of how two tissues (e.g., nerves and lungs) interact to build alveoli at the organismal level.

2022-06-16 | GSE189466 | GEO

Transcriptomic analysis of dynamic dysregulation in brainstem autonomic nuclei during the development of hypertension

Project description:Neurogenic hypertension stems from an imbalance in autonomic function that shifts the central cardiovascular control circuits towards a state of dysfunction. Using the female spontaneously hypertensive rat (SHR) and the normotensive Wistar Kyoto (WKY) rat model, we compared the transcriptomic changes in three autonomic nuclei in the brainstem, the nucleus of the solitary tract (NTS), caudal ventrolateral medulla (CVLM), and rostral ventrolateral medulla (RVLM) in a time series at 8, 10, 12, 16, and 24 weeks of age, spanning the pre-hypertensive stage through extended chronic hypertension.

2024-01-30 | GSE234784 | GEO

Leptin signaling maintains autonomic stability during severe influenza infection

Project description:Leptin signaling maintains autonomic stability during severe influenza infection

| PRJNA1147219 | ENA

Distinct roles of Hand2 in developing and adult autonomic neurons

Project description:Distinct roles of Hand2 in developing and adult autonomic neurons

| PRJNA419955 | ENA

Choice Architecture and Mailed Colorectal Cancer Screening Outreach in a Community Health Setting

Project description:This is a 3-arm randomized trial aimed at increasing rates of participation in colorectal cancer (CRC) screening by outreach to patients’ homes using choice architecture informed by behavioral science principles.

| 2364057 | ecrin-mdr-crc

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data