Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Streptomyces sclerotialus strain:NRRL ISP-5269

ABSTRACT: Streptomyces sclerotialus strain:NRRL ISP-5269 Genome sequencing

PROVIDER: PRJNA1097461 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Streptomyces cinereoruber strain:NRRL ISP-5012 | isolate:NRRL ISP-5012

Project description:Streptomyces cinereoruber cinereoruber NRRL ISP-5012 genome sequencing

| PRJNA581031 | ENA

Streptomyces fragilis strain:ISP 5044

Project description:Streptomyces fragilis strain:ISP 5044 Genome sequencing

| PRJNA943366 | ENA

Ribosome pausing at the AT-rich codons regulates the protein expression of secondary metabolite gene clusters in the Streptomyces tsukubaensis NRRL 18488

Project description:Streptomyces tsukubaensis NRRL 18488 is the preferred strain for the production of immunosuppressant agent tacrolimus (FK506). To take full advantage of its genetic potential, systematic understanding of secondary metabolism and related regulatory mechanisms is highly demanded. Here, to this end, we complete its 7.9 Mbp linear genome sequence followed by integrating with multi-omics measurements. With accurate reannotation of FK506 gene cluster, total 2,389 transcription start sites were determined by using primary transcriptome analysis. Integrated analysis of transcriptome and translatome data revealed that secondary metabolic gene clusters, especially FK506 cluster, undergo translational control with decrease in translational efficiency according to the growth. Furthermore, we demonstrated that SD motif has little correlation with ribosome pausing but AT-rich codons delay the translational elongation. Strong ribosome pausing was observed in the rare TTA codon in FK506 cluster. This comprehensive genome-scale analysis provides insight to the translational regulation of secondary metabolism in S. tsukubaensis.

2019-10-16 | GSE97637 | GEO

Streptomyces tsukubensis strain:NRRL 18488

Project description:Streptomyces tsukubensis strain:NRRL 18488 Genome sequencing

| PRJNA382016 | ENA

Streptomyces ficellus strain:NRRL 8067

Project description:Streptomyces ficellus strain:NRRL 8067 Genome sequencing

| PRJNA507930 | ENA

RNA-sequencing of C.elegans isp-1 mutant and superoxide dismutase-isp-1 double mutants

Project description:isp-1;sod double mutants have decreased lifespan, increased resistance to oxidative stress and slow physiologic rates. We performed RNA sequencing to compare gene expression between isp-1 mutants and isp-1;sod-3 and isp-1;sod-5 double mutants

2017-08-30 | GSE95240 | GEO

Streptomyces secondary metabolism

Project description:This project aims to discover novel bioactive compounds from Streptomyces isolated from the rhizosphere from wild medicinal plants from Hamedan province, Iran. Proteomics is used to assist in discovery and characterization of the compounds. Streptomyces isolates are grown on ISP-4 medium for three days, proteins were extracted and analysed by shotgun proteomics.

2024-01-04 | PXD041994 | Pride

Expression analysis of Candida tenuis NRRL Y-1498 grown in glucose or xylose

Project description:Investigation of whole genome gene expression level changes in Candida tenuis NRRL Y-1498 grown aerobically in xylose, compared to the same strain grown aerobically in glucose.

2011-10-20 | GSE24856 | GEO

Expression analysis of Lodderomyces elongisporus NRRL YB-4239 grown in glucose or xylose

Project description:Investigation of whole genome gene expression level changes in Lodderomyces elongisporus NRRL YB-4239 grown aerobically in xylose, compared to the same strain grown aerobically in glucose.

2011-10-20 | GSE24855 | GEO

Expression analysis of Spathaspora passalidarum NRRL Y-27907 grown in glucose or xylose

Project description:Investigation of whole genome gene expression level changes in Spathaspora passalidarum NRRL Y-27907 grown aerobically in xylose, compared to the same strain grown aerobically in glucose.

2011-10-20 | GSE24853 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data