Project description:We have isolated a likely bacterial pathogen from cerebrospinal fluid from a Ugandan infant suffering from hydrocephalus. Whole-genome sequencing and assembly of the genome of the clinical isolate, as well as that of a previously deposited reference strain, identified the isolate as Paenibacillus thiaminolyticus, which has not been associated with widespread human infections.

| S-EPMC7380522 | biostudies-literature

Transcriptome analysis reveals that sporulation is used as an iron deficiency resistance mechanism in Paenibacillus riograndensis SBR5

Project description:Transcriptome analysis of Paenibacillus riograndensis SBR5. SBR5 strain was grown in sufficient iron media and limited iron media.

2015-04-11 | E-GEOD-66816 | biostudies-arrayexpress

Peptide-based quorum sensing systems in Paenibacillus polymyxa

Project description:Paenibacillus polymyxa is an agriculturally important plant growth promoting rhizobacterium (PGPR). Many Paenibacillus species are known to be engaged in complex bacteria-bacteria and bacteria-host interactions, which in other bacteria were shown to necessitate quorum sensing communication, but to date no quorum sensing systems have been described in Paenibacillus. Here we show that the type strain P. polymyxa ATCC 842 encodes at least 16 peptide-based communication systems. Each of these systems comprises a pro-peptide that is secreted to the growth medium and further processed to generate a mature short peptide. Each peptide has a cognate intracellular receptor of the RRNPP family, and we show that external addition of P. polymyxa communication peptides to the medium leads to reprogramming of the transcriptional response. We found that these quorum sensing systems are conserved across hundreds of species belonging to the Paenibacillaceae family, with some species encoding more than 25 different peptide-receptor pairs, representing a record number of quorum sensing systems encoded in a single genome.

2020-08-05 | PXD015319 | Pride

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