Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Diversity of free-living amoeba in New Zealand groundwater

PROVIDER: PRJNA1134268 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29768628_1.fastq.gz	Fastqsanger.gz
	SRR29768629_1.fastq.gz	Fastqsanger.gz
	SRR29768630_1.fastq.gz	Fastqsanger.gz
	SRR29768631_1.fastq.gz	Fastqsanger.gz
	SRR29768632_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 11

Similar Datasets

Dictyostelium citrinum

Project description:A soil free-living amoeba

| PRJNA45941 | ENA

Candidatus Amoebophilus asiaticus 5a2

Project description:Obligate symbiont of a free-living amoeba

| PRJNA19981 | ENA

Project description:Transcriptome for the Free-Living Testate Amoeba Arcella intermedia

| PRJNA515423 | ENA

Gene expression in rabbit left atrial free wall and left atrial appendage

Project description:RNA sequencing of dissected left atrial free wall and left atrial appendage of adult New Zealand White rabbit

2018-10-19 | GSE117801 | GEO

Strand specific sequencing illustrates the complex transcriptional response of Legionella pneumophila during infection

Project description:Legionella pneumophila is a Gram-negative facultative intracellular human pathogen with a distinct biphasic lifestyle. One of its primary environmental hosts in the free-living amoeba Acanthamoeba castellanii and its infection by L. pneumophila mimics that seen in human macrophages. Here we present analysis of strand specific sequencing of the transcriptional response of L. pneumophila in broth growth and in infection of A. castellanii.

2011-02-11 | GSE27232 | GEO

Entamoeba moshkovskii

Project description:This free-living amoeba is closely related to Entamoeba hisotolytica

| PRJNA12920 | ENA

Strand specific sequencing illustrates the complex transcriptional response of Legionella pneumophila during infection

2011-02-11 | E-GEOD-27232 | biostudies-arrayexpress

Symbiont-mediated defense against Legionella pneumophila in amoebae

Project description:Legionella pneumophila are important opportunistic pathogens for which environmental reservoirs such as protists are crucial for the infection of humans. Free-living amoebae are considered key hosts providing nutrients and shelter for highly efficient intracellular proliferation of L. pneumophila, which eventually leads to lysis of the amoeba host cell. Yet, the significance of other bacterial players for L. pneumophila ecology is poorly understood. In this study we used a ubiquitous amoeba and their bacterial endosymbiont to investigate the impact of this common association on L. pneumophila infection. We demonstrate that Acanthamoeba castellanii harboring the chlamydial symbiont Protochlamydia amoebophila were able to erase L. pneumophila and, in contrast to symbiont-free amoebae, survived the infection and were able to resume growth. Environmental amoeba isolates harboring P. amoebophila were equally well-protected, and fresh environmental isolates of L. pneumophila were equally well-erased, suggesting ecological relevance of this symbiont-mediated protection. We further show that protection was not mediated by impaired L. pneumophila uptake. Instead, we observed reduced virulence of L. pneumophila released from symbiont-containing amoebae that is strongly supported by transcriptome data. Interference with transition to the transmissive phase is thus likely the basis for this protection. Finally, our data indicate that the defensive response of amoebae harboring P. amoebophila leaves the amoebae with superior fitness reminiscent of immunological memory. Given that mutualistic associations between bacteria and amoebae are widely distributed, P. amoebophila and potentially other amoeba endosymbionts could be key elements in shaping environmental survival, abundance and virulence of this important pathogen thereby affecting frequency of human infection.

2019-04-14 | GSE125876 | GEO

NZ Hexactinelllida

Project description:Diversity of New Zealand glass sponges

| PRJEB57794 | ENA

Project description:Bacterial bioclusters relate to hydrochemistry in New Zealand groundwater

| PRJNA485660 | ENA