Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Temporal dynamics of gene expression in Campylobacter jejuni biofilm formation

ABSTRACT: Temporal dynamics of gene expression in Campylobacter jejuni biofilm formation

PROVIDER: PRJNA1136887 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29863700_1.fastq.gz	Fastqsanger.gz
	SRR29863700_2.fastq.gz	Fastqsanger.gz
	SRR29863701_1.fastq.gz	Fastqsanger.gz
	SRR29863701_2.fastq.gz	Fastqsanger.gz
	SRR29863702_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 40

Similar Datasets

Temporal dynamics of gene expression in Campylobacter jejuni biofilm formation

Project description:Campylobacter jejuni, an important pathogen of bacterial gastrointestinal infections, forms biofilms that are crucial for its survival in different environments. We used RNA sequencing to investigate the changes in gene expression at different stages of biofilm formation (16 h, 24 h, 48 h and 72 h). The results showed that early biofilms (16 h and 24 h biofilms) show increased expression of genes involved in cysteine and methionine amino acid metabolism, while mature biofilms (48 h and 72 h biofilms) show decreased expression of capsular polysaccharides and lipooligosaccharides. Both early and mature biofilms are characterized by increased expression of genes involved in flagella formation, leucine amino acid metabolism and oxidative stress response, and decreased expression of genes involved in energy metabolism, iron acquisition and transmembrane transport. Thus, we provide a deeper understanding of the molecular mechanisms of C. jejuni biofilm maturation, environmental resistance and the dynamic nature of gene expression that facilitates adaptation to biofilm-associated lifestyles

2024-12-02 | GSE272440 | GEO

Campylobacter jejuni butyrate resopnse

Project description:Growth of Campylobacter jejuni in butyrate, including deletions of a TCS involved in sensing this response

2021-01-01 | GSE142852 | GEO

Diarrhoeal mechanisms of the Campylobacter jejuni enteritis

Project description:Campylobacter jejuni is the most prevalent cause of foodborne bacterial enteritis worldwide. This study aims at the characterisation of pathomechanisms and signalling in Campylobacter-induced diarrhoea in the human mucosa. During routine colonoscopy, biopsies were taken from patients suffering from campylobacteriosis. RNA-seq of colon biopsies was performed to describe Campylobacter jejuni-mediated effects. Mucosal mRNA profiles of acutely infected patients and healthy controls were generated by deep sequencing using Illumina HiSeq 2500. This data provide the basis for subsequent upstream regulator analysis.

2017-10-10 | GSE88710 | GEO

Campylobacter jejuni gene expression in germ-free mice

Project description:Expression arrays comparing Campylobacter jejuni NCTC11168 during growth in the cecum of germ-free C57 BL/6 IL-10 knockout mice to C. jejuni NCTC11168 during growth in Bolton broth.

2011-04-14 | GSE28578 | GEO

Transcriptional profile in macrolide susceptible and resistant Campylobacter jejuni

Project description:Campylobacter jejuni is a major zoonotic pathogen transmitted to humans via the food chain. C. jejuni is prevalent in chickens, a natural reservoir for this pathogenic organism. Due to the importance of macrolide antibiotics in clinical therapy of human campylobacteriosis, development of macrolide resistance in Campylobacter has become a concern for public health.To facilitate understanding the molecular basis associated with the fitness difference between Erys and Eryr Campylobacter, we compared the transcriptomes between ATCC 700819 and its isogenic Eryr transformant T.L.101 using DNA microarray.

2011-11-02 | GSE33330 | GEO

Campylobacter jejuni murine adaptation: unadapted v. adapted

Project description:Expression arrays comparing Campylobacter jejuni 11168 before and after serial passage in C57 BL/6 IL-10 deficient mice. Gene expression was compared during exponential growth in Bolton broth.

2009-08-08 | GSE17562 | GEO

Acanthamoeba castellanii as a model for unveiling Campylobacter jejuni host-pathogen dynamics

Project description:The persistence of Campylobacter jejuni in the natural environment, despite its microaerophilic nature, continues to be a subject of active investigation. Its survival and persistence likely stem from a combination of factors, including interactions with amoebae. C. jejuni transiently interacts with Acanthamoebae and this is thought to provide protection against unfavourable conditions and prime the bacteria for interactions with warm-blooded hosts. Acanthamoebae play vital roles in ecosystems by preying on microorganisms and establishing ecological niches with various bacterial species, some of which are clinically important pathogens. To gain a better understanding on the role of Acanthamoebae in the persistence of C. jejuni in the natural environment, we examined their interactions at the molecular level.

2024-06-28 | GSE262802 | GEO

Defining stationary phase transcriptomes of Campylobacter jejuni cell morphotypes

Project description:Filamentation, the transition from rod to filamentous cell morphology, has been identified as a response to stressful conditions in many bacterial species. Campylobacter jejuni exhibits filamentation upon entry to stationary phase. This study examines the cell mophotype specific transciptomes (RNAseq) of C. jejuni.

2018-07-07 | GSE116729 | GEO

Defining stationary phase transcriptomes of Campylobacter jejuni cell morphotypes II

2018-07-10 | GSE116814 | GEO

Gene Expression Changes in Campylobacter jejuni triggered by exposure to Novobiocin

Project description:In order to investigate the gene experssion changes in Campylobacter jejuni triggered by exposure to Novobiocin.

2009-12-28 | GSE18415 | GEO