Project description:Interventions: None: niet WMO-plichtig onderzoek.
Retrospective analysis of clinical and pathology records, and molecular analysis on resection specimen.
Primary outcome(s): 1. Prevalence of interval CRCs in a Dutch population;
2. Clinical characteristics;
3. Molecular characteristics;
4. Differences with non-interval CRCs.
Study Design: N/A: single arm study, N/A , unknown, Parallel
Project description:EMG produced TPA metagenomics assembly of the Molecular study on haloarchaea producing industerially important enzymes (Molecular study on Haloarchaea) data set
Project description:Interventions: 1. Clinical data registration;
2. Molecular analysis of polypoid vs. flat colorectal lesions.
Primary outcome(s): 1. Prevalence of flat colorectal lesions in a Dutch population;
2. Clinical characteristics (e.g. location of lesions, percentage of high-grade dysplasia or early cancer);
3. Molecular charcteristics (epigenetic: methylation status and genetic) of flat vs. polypoid colorectal lesions;
4. Prevalence of flat advanced colorectal cancers vs. polypoid advanced colorecal cancers: clinical features of these lesions (e.g. tumor stage);
5. Relation between serrated and adenomatous polyps.
Study Design: Non-randomized controlled trial, Open (masking not used), N/A , unknown, Factorial