Project description:We sequenced liver mRNA isolated from biliatresone-treated zebrafish larvae and DMSO-treated controls in order to elucidate the molecular pathways induced by biliatresone, a biliary toxin that is responsible for outbreaks of biliary atresia in Australian liverstock.
Project description:Mice were infected with Klebsiella pneumoniae and interstitial and alveolar macrophages isolated and subjected to single cell RNA sequencing to investigate the transcriptomes of Klebseilla-associated and uninfected bystander cells.
2022-09-16 | GSE184290 | GEO
Project description:Klebsiella and Raoultella from the marine environmnet
Project description:Klebsiella pneumoniae is a gram-negative bacterium that can cause lung disease in humans. Meanwhile, the contamination situation of Klebsiella pneumoniae in aquaculture environment is critical. In this study, we determined for the first time the growth of Klebsiella pneumoniae isolated from common edible aquatic products in different carbon sources.
Project description:Klebsiella pneumoniae is a gram-negative bacterium that can cause lung disease in humans. Meanwhile, the contamination situation of Klebsiella pneumoniae in aquaculture environment is critical. In this study, we determined for the first time the growth of Klebsiella pneumoniae isolated from common edible aquatic products in different carbon sources.
Project description:We report that Klebsiella pneumoniae promote Th1 cell induction in colon. To examine the influence of Klebsiella on colonic epithelial cells (ECs) and lamina propria CD11c+ dendritic cells (DCs), we performed RNA seq on them. Germ free mice were orally inoculated with Kp-2H7 or BAA-2552 and total RNA was isolated from colonic ECs and DCs 1 week after inoculation. Furthermore, we examined the involvement of TLRs in induction of Th1 cells using Myd88 KO, Trif KO, Myd88/Trif DKO mice. These deficient germ free mice were orally inoculated with Kp-2H7 and total RNA was isolated from colonic ECs 3 weeks after inoculation.
2017-10-20 | GSE101678 | GEO
Project description:Raoultella spp. isolated from animals in the UK
| PRJNA979912 | ENA
Project description:Mixed environmental consortia identified on Western Australian Monazite
