Project description:Visual deprivation, either in the form of dark rearing (DR) or monocular deprivation (MD) are established paradigms for studying cortical plasticity. We have used miRNA microarray to uncover miRNAs whose expression is altered in primary visual cortex following DR and/or MD. C57BL6 mice were reared in normal light and dark conditions (control) till P28, in complete darkness since birth (DR) till P28, or were grown in normal light/dark conditions from birth till P24 and then subjected to lid suturing of one eye till P28. Mice were euthanized at P28 and their primary visual cortex areas were excised and subjected to RNA isolation. In the case of MD mice only the contralateral to lid suture primary visual cortex was extracted. 100ng of total RNA (tested and quantified using the Agilent Bioanalyzer 2100) were labeled using the Agilent miRNA labeling system and hybridized to Agilent murine miRNA arrays. Microarrays were hybridized overnight at 64 ºC, scanned using an Agilent scanner and extracted with Agilent feature extractor 10.1.

2011-09-03 | E-GEOD-31536 | biostudies-arrayexpress

Depression mice primary visual cortex proteome

Project description:The project included proteomic data sets generated from samples of primary visual cortex of depressed mice and depressed mice receiving c-MSS physical therapy.

2022-02-11 | PXD031598 |

scRNA-seq for the monkey primary visual cortex

Project description:Transcriptomes of monkey primary visual cortex at the single-cell resolution. The dataset includes all cell types, including both glia and neurons.

2022-10-24 | E-MTAB-10459 | biostudies-arrayexpress

Astrocyte developmental transcriptome from mouse visual cortex

Project description:Analysis of astrocyte gene expression across postnatal development in the mouse visual cortex, spanning the time of synaptogenesis and synapse maturation.

2021-10-08 | GSE161398 | GEO

Astrocyte developmental transcriptome from mouse visual cortex

Project description:Astrocyte developmental transcriptome from mouse visual cortex

| PRJNA678219 | ENA

Layer 4 Visual Cortex Star Pyramid Monocular Deprivation Microarray Study

Project description:Microarray expression profiling of manually sorted m-citirin-labeled layer 4 visual cortex star pyramid neurons from deprived and non-deprived hemispheres. Monocular deprivation by TTX-injection (at P12-13 and again at P13-14), followed by manual sorting of m-Citrin-labeled Layer 4 Visual Cortex Star Pyramid neurons in deprived and non-deprived hemispheres. RNA was extracted using PicoPure RNA Isolation Kit, reverse transcribed, and amplified using a standard T7 IVT protocol (Affymetrix Small Sample Target Labeling Assay Version II).

2014-04-12 | E-GEOD-56758 | biostudies-arrayexpress

Transcription profiling of mouse P18, P24, P46, P104, and P46DR (dark reared) non-deprived vs. deprived visual cortex (GEO Super Series)

Project description:This SuperSeries is composed of the following subset Series:; GSE4263: P18 mouse non-deprived vs. deprived visual cortex; GSE4264: P24 mouse non-deprived vs. deprived visual cortex; GSE4265: P46 mouse non-deprived vs. deprived visual cortex; GSE4266: P104 mouse non-deprived vs. deprived visual cortex; GSE4267: P46DR (dark reared) mouse non-deprived vs. deprived visual cortex Experiment Overall Design: Refer to individual Series

2008-06-13 | E-GEOD-4269 | biostudies-arrayexpress

Astrocyte transcriptome from mouse visual cortex after different plasticity paradigms

Project description:Analysis of astrocyte gene expression after induction of plasticty in the mouse visual cortex, spanning the time of synapse maturation to adulthood.

2025-03-20 | GSE259341 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data