Danio rerio
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA122597 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Transcriptional Profiling of Zebrafish Embryonic Developmental Time Course
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Project description:Zebrafish are a tropical species of fish that inhabit streams that can fluctuate dramatically in temperature. In response to a decrease in temperature, the heart of zebrafish alters the structure of the myocardium and the expression of genes that code for proteins involved in contraction. Since very little is known about the processes supporting these changes in zebrafish, this study evaluated how the protein landscape of the ventricle changes with both an acute and a chronic decrease in temperature from 27oC to 20oC at multiple time points. this tested the hypothesis that a decrease in temperature would elicit changes in protein abundance and phosphorylation to maintain heart function. This study identified 1108, 1851, 1137, and 2325 phosphopeptides at each time point and 2052, 1656, 635, and 1530 proteins at each time point.
2024-10-15 | PXD049999 | Pride
Project description:Innate and adaptive immunity in zebrafish: time course (zebrafish)
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Project description:Ribosome Profiling over a Zebrafish Developmental Timecourse
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Project description:Wound healing process after TBI in zebrafish: time course (zebrafish)
| PRJNA243077 | ENA
Project description:Purpose: Construction of 3D zebrafish spatial transcriptomics data for studying the establishment of AP axis. Methods: We performed serial bulk RNA-seq data of zebrafish embryo at three development points. Using the published spatial transcriptomics data as references, we implemented Palette to infer spatial gene expression from bulk RNA-seq data and constructed 3D embryonic spatial transcriptomics. The constructed 3D transcriptomics data was then projected on zebrafish embryo images with 3D coordinates, establishing a spatial gene expression atlas named Danio rerio Asymmetrical Maps (DreAM). Results: DreAM provides a powerful platform for visualizing gene expression patterns on zebrafish morphology and investigating spatial cell-cell interactions. Conclusions: Our work used DreAM to explore the establishment of anteroposterior (AP) axis, and identified multiple morphogen gradients that played essential roles in determining cell AP positions. Finally, we difined a hox score, and comprehensively demonstrated the spatial collinearity of Hox genes at single-cell resolution during development.
2024-04-08 | GSE262578 | GEO
Project description:Wound healing process after ventricular resection in zebrafish: time course (zebrafish)
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