Project description:Gata6 regulates lung epithelial stem cell development and airway regeneration. Here, the expression profile of microRNA was investigated when Gata6 was depleted during lung development.

2011-03-01 | GSE25874 | GEO

Expression profiling of microRNA in mouse eye, lung and testicle tissue

Project description:microRNA profile in mouse eye, lung and testicle tissue

2020-08-10 | GSE146262 | GEO

MicroRNA expression data in human fetal lungs

Project description:Microarray data of human fetal lungs between 16-23 weeks of gestation. The results provide a general insight into the microRNA expression profile during the canalicular phase of lung development.

2015-11-26 | GSE58139 | GEO

MicroRNA expression data in mouse fetal lungs

Project description:Microarray data of mouse postnatal lungs between day 1 and 6 weeks of age. The results provide a general insight into the microRNA expression profile during the alveolar phase of lung development. We obtained lung tissue of healthy postnatal mice, 4-5 replicates at each time point. Time points were day1, day4, day7, day14, and day 42.

2013-11-26 | E-GEOD-41413 | biostudies-arrayexpress

microRNA profiling of myocardial infarction on a PI3K setting in mouse models

Project description:Cardiac hypertrophy can lead to heart failure, and is induced either by physiological stimuli eg postnatal development, chronic exrcise training or pathological stimuli eg pressure or volume overload. This data set looks at microRNA profiles in mouse models to examine whether phosphoinositide 3-kinase (p110 alpha isoform) activity is critical for the maintenance of cardiac function and long term survival in a seeting of heart failure (myocardial infarction). The significance and expected outcome are to recognise genes involved in models of heart failure and attempt to examine underlying regulator pathways involved in possible cardica maintenance in the PI3K mouse model. The matching mRNA gene expression profile (GSE7487) is examined to look for mRNA and microRNA interactions. miRNA expression correlates directly with cardiac function. PI3K regulon ameliorates cardiac stress. Keywords: microRNA profiling, regulatory pathway discovery, genotype comparison

2010-03-08 | GSE14267 | GEO

Alterations in bronchial airway microRNA expression for lung cancer detection

Project description:We have previously shown that gene-expression alterations in cytologically normal appearing bronchial epithelial cells can be used as a biomarker for lung cancer detection in smokers (Whitney et al., BMC Medical Genomics 2015; Silvestri et al., NEJM 2015). In this study, we have established that there are also alterations in bronchial microRNA-expression of smokers with lung cancer. Importantly, the performance of an existing bronchial mRNA-biomarker has been improved by integrating microRNA with mRNA expression.

2018-03-08 | GSE93284 | GEO

microRNA expression profile in mouse lung development

Project description:We performed miRNA and mRNA profiling over a 7-point time course, encompassing all recognized stages of lung development and explore dynamically regulated miRNAs and potential miRNA-mRNA interaction networks specific to mouse lung development

2010-08-17 | GSE21052 | GEO

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