Ontology highlight
ABSTRACT:
PROVIDER: PRJNA141277 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:The effect of Crem absence on gene expression in mouse liver.
| PRJNA153839 | ENA
Project description:The effect of Crem absence on gene expression in mouse testis.
| PRJNA153837 | ENA
Project description:The effect of Crem absence on gene expression in mouse adrenal glands.
| PRJNA153835 | ENA
Project description:Germ cells from adult mouse testes were isolated and ChIPed by CREM antibody. The purpose is to identify potential CREM targets during spermatogenesis.
2010-10-13 | GSE24623 | GEO
Project description:To assess a potential role of transcription factor CREM in the long-term detrimental effects of beta1-adrenoceptor overexpression, four mouse lines were generated and studied: wild-type mice (WT), Crem-normal beta1AR-transgenic mice (beta1ARTG), Crem-deficient non-transgenic mice (Crem-/-) and Crem-deficient beta1AR-transgenic mice (beta1ARTG/Crem-/-). We focused on genes up- or down-regulated in transgenic mice due to the lacking of CREM (beta1ARTG/Crem-/- vs. beta1ARTG).
2007-03-02 | E-MEXP-582 | biostudies-arrayexpress
Project description:Germ cells from adult mouse testes were isolated and ChIPed by CREM antibody. The purpose is to identify potential CREM targets during spermatogenesis. The CREM antibody ChIPed DNA segments were labeled with Cy5 and goat IgG ChIPed segments were labeled with Cy3 as control. No duplicates were designed.
2010-10-13 | E-GEOD-24623 | biostudies-arrayexpress
Project description:CREM (cAMP responsive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promoters of selected genes. CREM can produce isoforms that have either activating or repressing functions, depending on the transcription of specific exons. In testis, it is involved in the regulation of spermatogenesis. In this dataset, we include the expression data obtained from wild-type and Crem knock-out mouse testis. 2 condition experiment: 2 strains (WT, Crem-/-). 5 biological replications per condition.
2012-04-10 | E-GEOD-29593 | biostudies-arrayexpress
Project description:CREM (cAMP responsive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promoters of selected genes. CREM can produce isoforms that have either activating or repressing functions, depending on the transcription of specific exons. In adrenal glands it is involved in the regulation of expression of genes for steroid hormone synthesis. In this dataset, we include the expression data obtained from wild-type and Crem knock-out mouse adrenal glands. 2 condition experiment: 2 strains (WT, Crem-/-). 5 biological replications per condition.
2014-05-25 | E-GEOD-29592 | biostudies-arrayexpress
Project description:CREM (cAMP responsive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promoters of selected genes. CREM can produce isoforms that have either activating or repressing functions, depending on the transcription of specific exons. In adrenal glands it is involved in the regulation of expression of genes for steroid hormone synthesis. In this dataset, we include the expression data obtained from wild-type and Crem knock-out mouse adrenal glands.
2014-05-25 | GSE29592 | GEO
Project description:CREM (cAMP responsive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promoters of selected genes. CREM can produce isoforms that have either activating or repressing functions, depending on the transcription of specific exons. In this dataset, we include the expression data obtained from wild-type (WT) and Crem knock-out (KO) mouse liver. Several comparisons were made. KO<WT at 0h, KO<WT at 12 h, 0h<12h in WT and 0h<12h in KO. 4 condition experiment: 2 strains (WT, Crem-/-), 2 time points (0h and 12h). 5 biological replications per condition.
2014-05-25 | E-GEOD-29594 | biostudies-arrayexpress