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Drosophila melanogaster

ABSTRACT: Dorsal dependent CBP binding on a genome wide scale

PROVIDER: PRJNA149815 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR387933.fastq.gz	Fastqsanger.gz
	SRR387934.fastq.gz	Fastqsanger.gz
	SRR387935.fastq.gz	Fastqsanger.gz
	SRR387936.fastq.gz	Fastqsanger.gz

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Project description:We find a high concordance between the binding of the Drosophila transcription factor Dorsal and the co-activator CBP during early embryogenesis. This relationship was furter examined by comparing CBP distribution in Drosophila embryos derived from wt and mutant flies lacking intranuclear Dorsal (gd7). Our data suggests a specific involvemet of CBP in initiating early dorsoventral patterning, but not in anterioposterior. CBP ChIP seq of 2-4 hours old Drosophila embryos derived from w1118 (wild-type) or gd7 homozygous mutant mothers

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