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Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

ABSTRACT: Exposure of microaerobic Campylobacter jejuni to 10 micromolar NOC-5 & NOC-7

PROVIDER: PRJNA167401 | ENA |

REPOSITORIES: ENA

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Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Project description:Exposure of oxygen limited Campylobacter jejuni to 10 micromolar NOC-5 & NOC-7

| PRJNA167402 | ENA

Do globins in the microaerophile Campylobacter jejuni function in nitrosative stress tolerance under oxygen limitation?

Project description:This SuperSeries is composed of the following subset Series: GSE38114: Exposure of microaerobic Campylobacter jejuni to 10 micromolar NOC-5 & NOC-7 GSE38115: Exposure of oxygen limited Campylobacter jejuni to 10 micromolar NOC-5 & NOC-7 Refer to individual Series

2012-05-22 | E-GEOD-38116 | biostudies-arrayexpress

Differential RNA-sequencing of Campylobacter jejuni NCTC 11168

Project description:We report the use of differential RNA-sequencing for the determination of the primary transcriptome of wildtype Campylobacter jejuni NCTC 11168. This allows for the genome-wide determination of transcription start sites.

2013-09-13 | GSE49312 | GEO

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Project description:Exposure of microaerobic Campylobacter jejuni to diffusible molecules from chicken caecal contents

| PRJNA172023 | ENA

Campylobacter jejuni comparative genome: control strain C. jejuni subsp. jejuni ATCC 700819 (NCTC 11168) vs. 12 other strains

Project description:Gene content comparison of control C. jejuni subsp. jejuni strain 11168 which colonizes and causes disease in C57BL/6 IL-10-/- mice versus C. jejuni strains D6844, D6845, D6846, D6847, D6848, D6849, D0121, D0835, D2586, D2600,33560 and NW in the C57BL/6 IL-10-/- mice. Keywords: DNA/DNA comparison

2010-10-21 | GSE24764 | GEO

Identification of pH-specific protein expression responses by Campylobacter jejuni strain NCTC 11168

Project description:Campylobacter jejuni is one of the major causes of food-borne infections world-wide. The species is strictly host associated and tolerates mild levels of acidity and alkalinity. The ability to survive pH challenges is one of the key aspects of the ability of C. jejuni to survive in food, stomach transit and enables host gastrointestinal tract colonisation. In this study C. jejuni reference strain NCTC 11168 grown within its pH physiological normal growth range (pH 5.8, 7.0 and 8.0, = ~0.5 h-1) and exposed to pH 4.0 shock for 2 hours. Proteins extracted from biomass were quantified using a combined data dependent and independent acquisition label-free based approach with the aim to identify pH-dependent proteins that respond in a growth phase independent manner. It was discovered that gluconate 2-dehydrogenase GdhAB, NssR-regulated globins Cgb and Ctb, cupin domain protein Cj0761, cytochrome c protein CccC (Cj0037c), and phosphate-binding transporter protein PstB all show acidic pH dependent abundance increases but are not activated by sub-lethal acid shock. Glutamate synthase (GLtBD) and the MfrABC and NapAGL respiratory complexes were induced in cells grown at pH 8.0. The response to pH stress by C. jejuni is to bolster microaerobic respiration and at pH 8.0 this is assisted by accumulation of glutamate the conversion of which could bolster fumarate respiration. Global protein abundance reduction of proteins linked to growth and survival overalls aids cellular energy conservation thus preserving a similar growth rate.

2023-04-27 | PXD038249 | Pride

RNA-sequencing of Campylobacter jejuni NCTC 11168 wildtype and fur perR mutant

Project description:We report the use of RNA-seq analysis for the determination of RPKM transcript levels in wildtype and fur perR mutant of Campylobacter jejuni NCTC 11168. This allows for comparison of gene expression levels.

2014-07-01 | GSE49687 | GEO

Screening for novel immunogenic proteins of Campylobacter jejuni NCTC 11168

Project description:The screening of a cDNA derived expression library of Campylobacter jejuni NCTC 11168 expressed in E. coli using a fusion construct and specific HaloTag interaction to a modified surface is shown. 1536 different clones were screened including positive (hisJ, cjaA, peb1a) and negative (argC, pyrC, gapA) reference proteins. The goal of the screening was to identify potential novel immunogenic proteins from C. jejuni by selecting clones showing a high signal intensity in comparison to the known antigens used as positive markers. Afterwards, the most promising clones were sequenced to identify the gene and corresponding protein, and these proteins were then investigated further. Consequently, 22 novel immunogenic proteins could be identified.

2013-04-06 | GSE45268 | GEO

Transcriptional profiles of Campylobacter jejuni NCTC 11168 to 0.125mg/L erythromycin treatment

Project description:Erythromycin is the drug of choice to treat campylobacteriosis, but resistance to this antibiotic is rising. The adaptive mechanisms employed by Campylobacter jejuni to erythromycin treatment remain unknown. The aim of this study is to determine the molecular basis underlying Campylobacter’s immediate response to Ery treatment.

2013-10-10 | GSE43024 | GEO

Transcriptional profiles of Campylobacter jejuni NCTC 11168 to 4mg/L erythromycin treatment

2013-10-10 | GSE43023 | GEO