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Campylobacter jejuni subsp. jejuni CG8486

ABSTRACT: Leading cause of food poisoning

PROVIDER: PRJNA17055 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	AASY01.dat.gz	Other
	AASY01.fasta.gz	Fasta.gz
	AASY01.master.dat	Other
	AASY01.dat.gz	Other

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Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Project description:Leading cause of food poisoning (altered virulence strain)

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Campylobacter jejuni

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Transcriptomic changes of Campylobacter jejuni subsp. jejuni strain 81116 in water

Project description:Campylobacter jejuni is the leading cause of campylobacteriosis in the developed world. Although most cases are caused by consumption of contaminated meat, a significant proportion is caused by consumption of contaminated water. Some C. jejuni isolates are better than others at surviving in water, which suggests that these strains are better adapted to transmission by water than others. The aim of this study is to investigate this phenomenon further. CFU counts and viability assays showed that strain 81116 survives better than strain 81-176 in a defined freshwater medium at 4°C. Comparative transcriptomic profiling using microarray revealed that these strains respond differently to water. This series presents the transcriptome of strain 81116 in water.

2017-09-01 | GSE94930 | GEO

Transcriptomic changes of Campylobacter jejuni subsp. jejuni strain 81-176 in water

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Salmonella enterica subsp. enterica serovar Enteritidis str. LK5

Project description:Major cause of food poisoning in US

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Common genomic features of Campylobacter jejuni subsp. doylei strains distinguish them from C. jejuni subsp. jejuni.

Project description:BackgroundCampylobacter jejuni has been divided into two subspecies: C. jejuni subsp. jejuni (Cjj) and C. jejuni subsp. doylei (Cjd). Nearly all of the C. jejuni strains isolated are Cjj; nevertheless, although Cjd strains are isolated infrequently, they differ from Cjj in two key aspects: they are obtained primarily from human clinical samples and are associated often with bacteremia, in addition to gastroenteritis. In this study, we utilized multilocus sequence typing (MLST) and a DNA microarray-based comparative genomic indexing (CGI) approach to examine the genomic diversity and gene content of Cjd strains.ResultsA geographically diverse collection of eight Cjd strains was examined by MLST and determined to be phylogenetically distinct from Cjj strains. Microarray-based CGI approach also supported this. We were able to demonstrate that Cjd strains exhibited divergence from Cjj strains NCTC 11168 and RM1221 in many of the intraspecies hypervariable regions. Moreover, multiple metabolic, transport and virulence functions (e.g. cytolethal distending toxin) were shown to be absent in the Cjd strains examined.ConclusionOur data demonstrate that Cjd are phylogenetically distinct from Cjj strains. Using the CGI approach, we identified subsets of absent genes from amongst the C. jejuni genes that provide clues as to the potential evolutionary origin and unusual pathogenicity of Cjd.

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Complete Genome Sequence of Campylobacter jejuni subsp. jejuni ATCC 35925.

Project description:Here, we report the complete genome sequence of Campylobacter jejuni ATCC 35925, an avian isolate from Sweden. The genome gives insight into the ATCC 35925 strain's remarkable ability to tolerate copper and its permissiveness to plasmid transformation.

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Campylobacter jejuni genes contributing to acid adaptation

Project description:In order to cause disease, the food- and water-borne pathogen Campylobacter jejuni must face the extreme acidity of the host stomach as well as cope with pH fluctuations in the intestine. In the present study, C. jejuni NCTC 11168 was grown under mild acidic conditions mimicking those encountered in the intestine. The resulting transcriptional profiles revealed how this bacterium fine-tunes gene expression in response to acid stress. This adaptation involves differential expression of respiratory pathways, induction of genes for phosphate transport and repression of energy generation and intermediary metabolism genes. Keywords: acid shock; dose response; transcriptional response to 3 mild-acidic pH growth conditions (pH6.5, pH 6.0 and pH5.0)

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Listeria monocytogenes XFL0605

Project description:A major cause of food-poisoning

| PRJNA19793 | ENA