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Homo sapiens

ABSTRACT: Gene expression profiles induced by overexpression of PDEF in MCF10A mammary epithelial cell line

OTHER RELATED OMICS DATASETS IN: E-GEOD-40986

PROVIDER: PRJNA175498 | ENA |

REPOSITORIES: ENA

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Gene expression profiles induced by overexpression of PDEF in MCF10A mammary epithelial cell line

Project description:Recent studies suggest that PDEF is required for secretory cell differentiation in several epithelial tissues. To investigate PDEF in the mammary gland, we examined the effect of this transcription factor on gene expression using microarray based profiling of MCF-10A cells. These cells are non-transformed mammary epithelial cells that express protein and gene expression programs of basal epithelial cells and undetectable levels of endogenous PDEF. Bioinformatics analysis of the genes induced or repressed by PDEF overexpression in MCF10A cells revealed a striking effect on expression of luminal and myoepithelial cell markers.

2014-03-29 | GSE40986 | GEO

Gene expression profiles induced by overexpression of PDEF in MCF10A mammary epithelial cell line

2014-03-29 | E-GEOD-40986 | biostudies-arrayexpress

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Project description:Gene profiles induced by overexpression of wild-type and mutant Notch1 variants in MCF10A mammary epithelial cell line

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Project description:Gene expression profiles induced by shRNA-mediated knockdown of PDEF in MCF7 mammary epithelial cell line

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Project description:PDEF knockdown and overexpression in mammary epithelial cells

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Subtle alterations in DNA methylation patterns in normal cells in response to dietary stilbenoids

Project description:Genome wide DNA methylation profiling of human mammary epithelial MCF10A cell line treated with vehicle control (ethanol) and with RSV (resveratrol). The Illumina Infinium 450K Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 450,000 CpGs in human cell lines exposed to described treatments. Samples included biological triplicate of MCF10A control (ethanol treated), biological triplicate of MCF10A treated with RSV.

2022-01-31 | GSE113299 | GEO

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Project description:Gene expression profiles induced by knockdown and overexpression of p63 variants in MCF-10A mammary epithelial cell line

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Project description:SNAI1 overexpression effect on MCF-10A mammary epithelial cell line (miRNA)

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Project description:SNAI1 overexpression effect on MCF-10A mammary epithelial cell line (mRNA)

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Timecourse total transcriptome sequencing of MCF10A cells undergoing acinus formation.

Project description:RNA-seq was performed for transcriptional analysis of MCF10A cells, an epithelial mammary cell line. MCF10A cells were cultured in 3D acinus forming conditions (in Matrigel). Timepoints analysed were 24h, 34h, 36h, 38h and 48h into acinus formation. Control cells were monoloayer.

2014-10-02 | E-MTAB-2969 | biostudies-arrayexpress

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