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Rattus norvegicus

ABSTRACT: 0.01X assembly of a wild rat by the European STAR Consortium

PROVIDER: PRJNA18695 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	AAXO01.dat.gz	Other
	AAXO01.fasta.gz	Fasta.gz
	AAXO01.master.dat	Other
	AAXO01.dat.gz	Other

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Rattus norvegicus strain:GK/Ox

Project description:0.01X assembly of rat strain GK/Ox by the European STAR Consortium

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Molecular complexity of the major urinary protein system of the Norway rat, Rattus norvegicus C4PR_LIV

Project description:Major urinary proteins (MUP) are the major component of the urinary protein fraction in house mice (Mus spp.) and rats (Rattus spp.). The structure, polymorphism and functions of these lipocalins have been well described in the western European house mouse (Mus musculus domesticus), clarifying their role in semiochemical communication. The complexity of these roles in the mouse raises the question of similar functions in other rodents, including the Norway rat, Rattus norvegicus. Norway rats express MUPs in urine but information about specific MUP isoform sequences and functions is limited. In this study, we present a detailed molecular characterization of the MUP proteoforms expressed in the urine of two laboratory strains, Wistar Han and Brown Norway, and wild caught animals, using a combination of manual gene annotation, intact protein mass spectrometry and bottom-up mass spectrometry-based proteomic approaches. Detailed sequencing of the urinary MUP isoforms reveals a less complex pattern of primary sequence polymorphism in the rat than the mouse. However, rat MUPs exhibit added complexity in the form of post-translational modifications, including the phosphorylation of Ser4 in some isoforms, and exoproteolytic trimming of specific isoforms.

2019-08-01 | PXD013986 | Pride

Rattus norvegicus

Project description:Genome sequencing by Rat Genome Sequencing Consortium

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Transcriptome Profiling of Rattus norvegicus Embryonic Stem Cells by RNA-Sequencing

Project description:In order to establish a rat embryonic stem cell transcriptome, mRNA from rESC cell line DAc8, the first male germline competent rat ESC line to be described and the first to be used to generate a knockout rat model was characterized using RNA sequencing (RNA-seq) analysis.

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Localization of dimethylated histone three lysine four in the Rattus norvegicus sperm genome

Project description:We examined the precise localization of dimethylated histone three lysine four (H3K4me2) in mature rat sperm.

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Radiation effects on gene expression in rat testes (Rattus norvegicus)

Project description:Analysis of LBNF1 rat testes from controls, containing both somatic and all germ cell types and from irradiated rats in which all cells germ cells except type A spermatgogonia are eliminated. Results provide insight into distinguishing germ and somatic cell genes and identification of somatic cell genes that are upregulated after irradiation.

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