Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

ABSTRACT: CompleteGenomics sequencing of (PJL) Puerto Rican in Puerto Rico HapMap population DNA for sequencing was extracted from whole blood

PROVIDER: PRJNA194111 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR1045041_1.fastq.gz	Fastqsanger.gz
	SRR1045041_2.fastq.gz	Fastqsanger.gz
	SRR1045042_1.fastq.gz	Fastqsanger.gz
	SRR1045042_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 143

Similar Datasets

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

Project description:CompleteGenomics sequencing of (PUR) Puerto Rican in Puerto Rico HapMap population DNA for sequencing was extracted from whole blood

| PRJNA194108 | ENA

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

Project description:CompleteGenomics sequencing of (PUR) Puerto Rican in Puerto Rico

| PRJNA177966 | ENA

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

Project description:Exome sequencing of (PUR) Puerto Rican in Puerto Rico HapMap population

| PRJNA59817 | ENA

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

Project description:Exome sequencing of (PUR) Puerto Rican in Puerto Rico HapMap population. DNA for sequencing was extracted from whole blood

| PRJNA196422 | ENA

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

Project description:Whole genome sequencing of (PUR) Puerto Rican in Puerto Rico HapMap population

| PRJNA42573 | ENA

Homo sapiens strain:(PUR) Puerto Rican in Puerto Rico

Project description:Whole genome sequencing of (PUR) Puerto Rican in Puerto Rico HapMap population DNA for sequencing was extracted from whole blood

| PRJNA177403 | ENA

Protein and cytokine profiles associated with COVID-19 disease severity in Puerto Rico

Project description:Viral strains, age, and host factors including genetics and proteins are associated with variable immune responses against SARS-CoV-2 and disease severity. We hypothesized that unique proteins/pathways are associated with COVID-19 disease severity in Puerto Rican Hispanics. A total of 121 men and women aged 21-80 years-old were recruited in Puerto Rico. Plasma samples were collected from unvaccinated COVID-19 infected subjects during acute disease (n=39) and compared to COVID-19 negative individuals (n=56) during acute disease using proteomics and cytokine expression. Infected individuals were stratified based on symptomatology as follows: mild (n=18), moderate (n=13), and severe (n=8). Quantitative proteomics was performed in plasma samples using Tandem Mass Tag (TMT) labeling. Cytokines in plasma were quantified using a human cytokine array. Proteomics analyses revealed 56 differentially regulated proteins and the top 3 pathways that were predicted to be inhibited in severe patients including LXR/RXR signaling, Production of NO and ROS in macrophages, and Synaptogenesis signaling. Decreased cadherin-13 validated by ELISA, which participates in synaptogenesis, is a novel protein is a novel protein not previously reported in other studies of COVID-19 severity and validated by ELISA. Cytokine analyses showed that TNF⍺ levels decreased with disease severity. This study uncovers potential host predictors of COVID-19 severity and new avenues for treatment in Puerto Rican Hispanics.

2024-06-16 | PXD046103 | Pride

Org.one project - Puerto Rican Parrot

Project description:Org.one project - Puerto Rican Parrot

| PRJEB72706 | ENA

Schistosoma mansoni isolate:Puerto Rican

Project description:Schistosoma mansoni isolate:Puerto Rican Raw sequence reads

| PRJNA302212 | ENA

Puerto Rican Parrot Genome

Project description:A Locally Funded Puerto Rican Parrot (Amazona vittata) Genome Sequencing Project

| PRJEB225 | ENA