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Anopheles sinensis

ABSTRACT: Anopheles sinensis Genome sequencing and assembly

PROVIDER: PRJNA209295 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR1574903.fastq.gz	Fastqsanger.gz
	SRR1574904.fastq.gz	Fastqsanger.gz
	SRR1574905.fastq.gz	Fastqsanger.gz
	SRR1574906.fastq.gz	Fastqsanger.gz

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Project description:We profile transcriptome-wide m6A in female and male Anopheles sinensis and reveal that m6A is also a highly conserved modification of mRNA in mosquitoes were generated by deep sequencing, in triplicate, using illumina Novaseq™ 6000. Distinct from mammals and yeast, but similar to Arabidopsis thaliana, m6A in An. sinensis is enriched not only around the stop codon and within 3’-untranslated regions, but also around the start codon and 5’-UTR. Gene ontology analysis indicates that the unique distribution pattern of m6A in An. sinensis is associated with mosquito sex-specific pathways. In addition, the positive correlation between m6A deposition and mRNA abundance indicates that m6A can play roles in regulating gene expression in mosquitoes. Our study proposed a transcriptional regulatory network of m6A in An. sinensis, which may provide a new clue for the control of this disease-transmitting vector.

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