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Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

ABSTRACT: The transcriptional landscape of Campylobacter jejuni under iron replete and iron limited growth conditions

PROVIDER: PRJNA211829 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR943033_1.fastq.gz	Fastqsanger.gz
	SRR943033_2.fastq.gz	Fastqsanger.gz
	SRR943058_1.fastq.gz	Fastqsanger.gz
	SRR943058_2.fastq.gz	Fastqsanger.gz
	SRR943059_1.fastq.gz	Fastqsanger.gz

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Differential RNA-sequencing of Campylobacter jejuni NCTC 11168

Project description:We report the use of differential RNA-sequencing for the determination of the primary transcriptome of wildtype Campylobacter jejuni NCTC 11168. This allows for the genome-wide determination of transcription start sites.

2013-09-13 | GSE49312 | GEO

Genomic and Proteomic Characterization of Sessile and Planktonic Campylobacter jejuni NCTC 11168

Project description:In order to understand the cellular mechanisms that facilitate a surface-associated lifestyle, expression profiles were determined at the levels of transcription and translation for sessile and planktonic Campylobacter jejuni NCTC 11168 (obtained from American Type Culture Collection (ATCC 700819)). These investigations indicate that the immobilized bacteria undergo a shift in cellular priorities away from metabolic, motility and protein synthesis capabilities towards emphasis on iron uptake, oxidative stress defense and membrane transport. Keywords: transcript profiling

2005-07-29 | GSE3028 | GEO

Global transcriptional analysis of Campylobacter jejuni NCTC 11168 in response to epinephrine and norepinephrine.

Project description:During colonization in the host gastrointestinal tract, the enteric bacteria Campylobacter jejuni is exposed to a variety of signaling molecules including the catecholamine hormones epinephrine (Epi) and norepinephrine (NE). NE has been determined to stimulate the growth of C. jejuni as well as increase its pathogenicity. To investigate the mechanisms of NE or Epi on the biology of C. jejuni, the global gene expression profiles of C. jejuni NCTC 11168 cultured in iron-restricted medium were analyzed in response to NE or Epi. Totally, 183 and 156 genes were differentially expressed by NE and Epi respectively, with 102 differentially expressed genes common between the two treatments. These genes are involved in diverse cellular functions including iron uptake systems, motility, virulence, oxidative stress response, nitrosative stress tolerance, enzyme metabolism, DNA repair and metabolism and ribosomal protein biosynthesis. Adherence to and invasion of Caco-2 cells by C. jejuni were enhanced upon exposure to NE or Epi. These results indicated that NE and Epi have similar effects on the gene expression of C. jejuni and that the effects on gene expression may contribute to elucidate the mechanisms on interaction between host and C. jejuni.

2015-02-10 | GSE65187 | GEO

Campylobacter jejuni comparative genome: control strain C. jejuni subsp. jejuni ATCC 700819 (NCTC 11168) vs. 12 other strains

Project description:Gene content comparison of control C. jejuni subsp. jejuni strain 11168 which colonizes and causes disease in C57BL/6 IL-10-/- mice versus C. jejuni strains D6844, D6845, D6846, D6847, D6848, D6849, D0121, D0835, D2586, D2600,33560 and NW in the C57BL/6 IL-10-/- mice. Keywords: DNA/DNA comparison

2010-10-21 | GSE24764 | GEO

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Project description:Exposure of oxygen limited Campylobacter jejuni to 10 micromolar NOC-5 & NOC-7

| PRJNA167402 | ENA

RNA-sequencing of Campylobacter jejuni NCTC 11168 wildtype and fur perR mutant

Project description:We report the use of RNA-seq analysis for the determination of RPKM transcript levels in wildtype and fur perR mutant of Campylobacter jejuni NCTC 11168. This allows for comparison of gene expression levels.

2014-07-01 | GSE49687 | GEO

Screening for novel immunogenic proteins of Campylobacter jejuni NCTC 11168

Project description:The screening of a cDNA derived expression library of Campylobacter jejuni NCTC 11168 expressed in E. coli using a fusion construct and specific HaloTag interaction to a modified surface is shown. 1536 different clones were screened including positive (hisJ, cjaA, peb1a) and negative (argC, pyrC, gapA) reference proteins. The goal of the screening was to identify potential novel immunogenic proteins from C. jejuni by selecting clones showing a high signal intensity in comparison to the known antigens used as positive markers. Afterwards, the most promising clones were sequenced to identify the gene and corresponding protein, and these proteins were then investigated further. Consequently, 22 novel immunogenic proteins could be identified.

2013-04-06 | GSE45268 | GEO

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Project description:Refined analysis of the Campylobacter jejuni iron-dependent/independent Fur- and PerR-transcriptomes

| PRJNA255798 | ENA

Transcriptional profiles of Campylobacter jejuni NCTC 11168 to 0.125mg/L erythromycin treatment

Project description:Erythromycin is the drug of choice to treat campylobacteriosis, but resistance to this antibiotic is rising. The adaptive mechanisms employed by Campylobacter jejuni to erythromycin treatment remain unknown. The aim of this study is to determine the molecular basis underlying Campylobacter’s immediate response to Ery treatment.

2013-10-10 | GSE43024 | GEO

Transcriptional profiles of Campylobacter jejuni NCTC 11168 to 4mg/L erythromycin treatment

2013-10-10 | GSE43023 | GEO