Ontology highlight
ABSTRACT:
PROVIDER: PRJNA213637 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia (miRNA)
| PRJNA213638 | ENA
Project description:Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia (mRNA)
| PRJNA213639 | ENA
Project description:Integrated ordination of miRNA and mRNA expression profiles [mRNA]
2020-11-27 | E-GEOD-62029 | ExpressionAtlas
Project description:The aim of this study was to determine the role that miRNAs have on influencing murine microgial phenotypes under M1(LPS) and M2a (IL-4) stimulating conditions. This Series includes expression data obtained from miRNA gene expression microarrays; mRNA expression profiles obtained from the same RNA samples were deposited as a separate Series. 9 total samples were analyzed, n=3 for the three stimulating conditions (resting state, LPS and IL-4) for murine primary microglia. This allowed us to perform the following pairwise comparisons: PBS vs. LPS, and PBS vs. IL-4. This was performed for both mRNA and miRNA gene expression profiles.
2014-03-13 | E-GEOD-49330 | biostudies-arrayexpress
Project description:The aim of this study was to determine the role that miRNAs have on influencing murine microgial phenotypes under M1(LPS) and M2a (IL-4) stimulating conditions. This Series includes expression data obtained from mRNA gene expression microarrays; miRNA expression profiles obtained from the same RNA samples were deposited as a separate Series. 9 total samples were analyzed, n=3 for the three stimulating conditions (resting state, LPS and IL-4) for murine primary microglia. This allowed us to perform the following pairwise comparisons: PBS vs. LPS, and PBS vs. IL-4. This was performed for both mRNA and miRNA gene expression profiles.
2014-03-13 | E-GEOD-49329 | biostudies-arrayexpress
Project description:Integrated ordination of miRNA and mRNA expression profiles [miRNA]
| PRJNA263012 | ENA
Project description:Integrated ordination of miRNA and mRNA expression profiles [mRNA]
| PRJNA263013 | ENA
Project description:Intervention type:DRUG. Intervention1:Huaier, Dose form:GRANULES, Route of administration:ORAL, intended dose regimen:20 to 60/day by either bulk or split for 3 months to extended term if necessary. Control intervention1:None.
Primary outcome(s): For mRNA libraries, focus on mRNA studies. Data analysis includes sequencing data processing and basic sequencing data quality control, prediction of new transcripts, differential expression analysis of genes. Gene Ontology (GO) and the KEGG pathway database are used for annotation and enrichment analysis of up-regulated genes and down-regulated genes.
For small RNA libraries, data analysis includes sequencing data process and sequencing data process QC, small RNA distribution across the genome, rRNA, tRNA, alignment with snRNA and snoRNA, construction of known miRNA expression pattern, prediction New miRNA and Study of their secondary structure Based on the expression pattern of miRNA, we perform not only GO / KEGG annotation and enrichment, but also different expression analysis.. Timepoint:RNA sequencing of 240 blood samples of 80 cases and its analysis, scheduled from June 30, 2022..
| 2612481 | ecrin-mdr-crc
Project description:Upon lipopolysaccharide (LPS) or interleukin-4 stimulation to trigger M1 or M2 polarized states respectively, label-free quantitative mass spectrometry (LFQ-MS) revealed novel state-specific proteomic profiles of microglia-derived exosomes.
2024-10-30 | PXD056226 | Pride