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Mus musculus

ABSTRACT: Delineating Tumor-infiltrating Antigen Presenting Cell populations

PROVIDER: PRJNA261162 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1575620.fastq.gz	Fastqsanger.gz
	SRR1575621.fastq.gz	Fastqsanger.gz
	SRR1575612.fastq.gz	Fastqsanger.gz
	SRR1575622.fastq.gz	Fastqsanger.gz
	SRR1575613.fastq.gz	Fastqsanger.gz

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Delineating Tumor-infiltrating Antigen Presenting Cell populations

Project description:The goal of this study is to compare tumor-infiltrating antigen presenting cell populations by global transcriptome profiling (RNA-seq) to help further delineate sub-populations of infiltrating myeloid cells in tumor. Methods: Four tumor antigen presenting cell populations were sorted from digested B78chOVA (melanoma variant) tumors in biological triplicate Results: RNA was extracted from the 4 groups (n=3 per group) and prepared for RNAseq. Sequencing yielded ~405 million reads with an average read depth of 33.7 million reads/sample. Reads were then aligned to the mouse genome (UCSC mm10) and those that mapped uniquely to known mRNAs were used to assess differential expression.

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