Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profile of C. elegans following RNAi of elt-2

ABSTRACT: Transcriptional profile of C. elegans following RNAi of elt-2

PROVIDER: PRJNA285038 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional profile of C. elegans following RNAi of elt-2 [L4 stage]

Project description:We used RNA-seq to identify 292 genes that are differentially-regulated following elt-2 RNAi

2016-03-22 | GSE69262 | GEO

Transcriptional profile of C. elegans following RNAi of elt-2 [L1 stage]

Project description:We used RNA-seq to identify 162 genes that are differentially-regulated following elt-2 RNAi

2016-03-22 | GSE69261 | GEO

Transcriptional profile of C. elegans following RNAi of elt-2 [L4 stage]

Project description:We used RNA-seq to identify 292 genes that are differentially-regulated following elt-2 RNAi Whole-worm mRNA was sequenced from elt-2 RNAi- and control-fed worms. Biological triplicates were assay for each condition

2016-03-22 | E-GEOD-69262 | biostudies-arrayexpress

Transcriptional profile of C. elegans following RNAi of elt-2 [L1 stage]

Project description:We used RNA-seq to identify 162 genes that are differentially-regulated following elt-2 RNAi Whole-worm mRNA was sequenced from elt-2 RNAi- and control-fed worms. Biological triplicates were assay for each condition

2016-03-22 | E-GEOD-69261 | biostudies-arrayexpress

Caenorhabditis elegans

Project description:Transcriptional profile of C. elegans following RNAi of elt-2 [L4 stage]

| PRJNA285044 | ENA

Caenorhabditis elegans

Project description:Transcriptional profile of C. elegans following RNAi of elt-2 [L1 stage]

| PRJNA285043 | ENA

Genome wide RNA Sequencing of whole C. elegans RNA

Project description:We report genes induced under transient hypoxia in an ELT-2 dependent manner Adult C. elegans were exposed to transient hypoxia and fed ELT-2 RNAi. Normoxia and Empty Vector RNAi were performed as controls

2014-08-27 | E-GEOD-60825 | biostudies-arrayexpress

Transcriptional profile of C. elegans fed E. coli (OP50) and B. subtilis (PY79)

Project description:We used RNA-seq to assay gene expression changes over time in response to OP50 and PY79 To understand the molecular processes underlying aging, we screened modENCODE ChIP-seq data to identify transcription factors that bind to age-regulated genes in C. elegans. The most significant hit was the GATA transcription factor encoded by elt-2, which is responsible for inducing expression of intestinal genes during embryogenesis. Expression of ELT-2 decreases during aging, beginning in middle age. We identified genes regulated by ELT-2 in the intestine during embryogenesis, and then showed that these developmental genes markedly decrease in expression as worms grow old. Overexpression of elt-2 extends lifespan and slows the rate of gene expression changes that occur during normal aging. Thus, our results identify the developmental regulator ELT-2 as a major driver of normal aging in C. elegans.

2016-03-22 | GSE79415 | GEO

Transcriptional profile of C. elegans fed E. coli (OP50) and B. subtilis (PY79)

2016-03-22 | E-GEOD-79415 | biostudies-arrayexpress

Total Proteome Analysis in RNAi treated C. elegans

Project description:A SWATH-based worflow has been developed for C. elegans proteome profiling, including sample preparation, SWATH spectral library generation and downstream data treatment. The influence of mrps-5 RNAi treatment on C. elegans total proteome were studied.

2019-12-11 | PXD009223 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data