Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Genome-wide binding profiles of Sp5 in differentiation mouse embryonic stem cells

PROVIDER: PRJNA295527 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR2392540.fastq.gz	Fastqsanger.gz
	SRR2392541.fastq.gz	Fastqsanger.gz
	SRR2392542.fastq.gz	Fastqsanger.gz
	SRR2392539.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Genome-wide binding profiles of Sp5 in differentiation mouse embryonic stem cells

Project description:We have determined the genome-wide binding profile of the transcription factor Sp5. Flag-tagged Sp5 was targeted to the HPRT locus in A2Lox.cre ES cells to allow for Doxycycline inducible expression. ES cells were cultured as embryoid bodies for 2 days to prime them for germ layer differentiation. Cells were then treated with Doxycycline for 24 hrs. We found that Flag-Sp5 prefentially bound to promoters associatd with several growth factor signalling pathways, but most prominently with the Wnt/beta-catenin pathway to selectively promote mesoderm differentiation over neural. These data implicate Sp5 as new regulator of Wnt/beta-catenin target expression to promotes ES cell differentation into the mesoderm lineage. Examination of Sp5 transcription factor binding in differentiating embryonic stem cells.

2016-04-01 | E-GEOD-72989 | biostudies-arrayexpress

Mus musculus

Project description:Genome-wide transcriptome profiles in pluripotent mouse Embryonic Stem Cells and during Retinoic Acid-induced differentiation

| PRJNA274740 | ENA

Mus musculus

Project description:Genome-wide binding profiles of nuclear FGFR1, RXRα and Nur77 in pluripotent mouse Embryonic Stem Cells and during Retinoic Acid-induced differentiation

| PRJNA274739 | ENA

Mus musculus

Project description:Genome-wide microRNA transcriptome profiles in pluripotent mouse Embryonic Stem Cells and during Retinoic Acid-induced differentiation

| PRJNA274738 | ENA

Mus musculus

Project description:Genome-wide Sall1 and Nanog binding sites in mouse embryonic stem cells

| PRJNA133989 | ENA

Mus musculus

Project description:Guided differentiation of mouse embryonic stem cell

| PRJNA104825 | ENA

Mus musculus

Project description:Random differentiation of mouse embryonic stem cell

| PRJNA104823 | ENA

Mus musculus

Project description:Genome-wide analysis of Embryonic Stem Cell Differentiation