Project description:Investigation of whole genome expression level changes in Bacillus anthracis Sterne deltaClpX mutant compared to the wild-type strain after growth in nutrient rich media. The deltaClpX mutant used in this study is described in McGillivray et al. 2009. ClpX Protease Contributes to Antimicrobial Peptide Resistance and Virulence Phenotypes of Bacillus anthracis. Journal of Innate Immunity 1(5): 494-506.
Project description:Bacillus anthracis Sterne 34F2 cells were grown in the absence of and in the presence of different concentrations of paraquat and hydrogen peroxide. Additionally, a deletion mutant strain lacking the sodA1 gene was also assayed with and without the addition of different concentrations of paraquat.