Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Enterobacter asburiae

ABSTRACT: Dissemination and characteristics of a novel carbapenem-hydrolysing class D β-lactamase, OXA-436 identified in different Enterobacteriaceae

PROVIDER: PRJNA297498 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	LLJM01.dat.gz	Other
	LLJM01.fasta.gz	Fasta.gz
	LLJM01.master.dat	Other
	LLJN01.dat.gz	Other
	LLJN01.fasta.gz	Fasta.gz

Items per page:

1 - 5 of 24

Similar Datasets

First dataset - bacterial proteome of carbapanemase-producing Escherichia coli and other Enterobacteriaceae under antibiotic pressure

Project description:Antibiotic resistance associated with the expression of the clinically significant carbapenemases, IMP, KPC, and NDM and OXA-48 in Enterobacteriaceae is emerging as a worldwide calamity to health care. In Australia, IMP-producing Enterobacteriaceae is the most prevalent carbapenemase-producing Enterobacteriaceae (CPE). Genomic characteristics of such carbapenemase-producing Enterobacteriaceae (CPE) are well described, but the corresponding proteome is poorly characterised. We have thus developed a method to analyse dynamic changes in the proteome of CPE under antibiotic pressure. Specifically, we have investigated the effect of meropenem at sub-lethal concentrations to develop a better understanding of how antibiotic pressure leads to resistance. Escherichia coli, producing either NDM, IMP or KPC type carbapenemase were included in this study, and their proteomes were analysed in growth conditions with or without meropenem.

2018-07-11 | PXD008019 | Pride

Enterobacter asburiae ST229: an emerging carbapenemases producer.

Project description:Enterobacter asburiae, member of the Enterobacter cloacae complex (ECC) group, shows an increasing clinical relevance being responsible for infections like pneumonia, urinary tract infections and septicemia. The aim of the present study was the investigation of the genomic features of two XDR E. asburiae ST229 clinical strains co-carrying blaNDM-1 and blaVIM-1 determinants, collected in October 2021 and in June 2022, respectively. Two E. asburiae strains were collected from rectal swabs of as many patients admitted to the cardiopulmonary intensive care unit of Fondazione I.R.C.C.S. "Policlinico San Matteo" in Pavia, Italy. Based on the antibiotic susceptibility profile results, both isolates showed an XDR phenotype, retaining susceptibility only to fluoroquinolones. Both isolates shared identical resistome, virulome, plasmid content, and belonged to ST229, a rarely reported sequence type. They co-harbored blaNDM-1 and blaVIM-1 genes, that resulted located on transferable plasmids by conjugation and transformation. Moreover, both strains differed in 24 SNPs and showed genetic relatedness with E. asburiae ST709 and ST27. We described the first case of ST229 E. asburiae co-harboring blaNDM-1 and blaVIM-1 in Italy. This study points out the emergence of carbapenemases in low-risk pathogens, representing a novel challenge for public health, that should include such types of strains in dedicated surveillance programs. Antimicrobial susceptibility testing was carried out using Thermo Scientific™ Sensititre™ Gram Negative MIC Plates DKMGN. Both strains underwent whole-genome sequencing (WGS) using Illumina Miseq platform. Resistome, plasmidome, virulome, MLST, plasmid MLST and a SNPs-based phylogenetic tree were in silico determined.

| S-EPMC10940580 | biostudies-literature

Enterobacter cloacae strain:ZZEN611

Project description:novel CTX-M-3-like β-lactamase found in Enterobacteriaceae

| PRJNA335696 | ENA

Complete Genome Sequence of a Clinical Isolate of Enterobacter asburiae.

Project description:We report here the complete genome sequence of Enterobacter asburiae strain ENIPBJ-CG1, isolated from a bone marrow transplant patient. The size of the genome sequence is approximately 4.65 Mb, with a G+C content of 55.76%, and it is predicted to contain 4,790 protein-coding genes.

| S-EPMC4901228 | biostudies-literature

Escherichia coli strain:EC-JS316

Project description:Characterisation of OXA-484, an OXA-48-type carbapenemhydrolysing class D beta-lactamase from E. coli

| PRJNA644256 | ENA

Enterobacter asburiae

Project description:Enterobacter asburiae Genome sequencing

| PRJNA813899 | ENA

Enterobacter asburiae

Project description:Characterization of temocillin resistance among Enterobacter asburiae clinical isolates

| PRJNA902787 | ENA

Enterobacter asburiae

Project description:Enterobacter asburiae Genome sequencing and assembly