Project description:To investigate the relationship between the expression of the UPR (unfolded protein response) genes, and the SARS-CoV-2 infection, a study was carried out based on the infection of hamster, Mesocricetus auratus. UPR gene levels were compared between infected and uninfected hamsters at different temporal points.
Project description:Transcriptional profiling by next generation sequencing of the spleen and splenic macrophages in the hamster model of visceral leishmaniasis
Project description:Non–alcoholic fatty liver disease (NAFLD) is high prevalent in worldwide and associated with chronic kidney disease (CKD). Infection with Opisthorchis viverrini (Ov) infection and consumption of high fat and high fructose (HFF) exacerbates NAFLD to nonalcoholic steatohepatitis in hamsters. Here, we aimed to investigate the effect a combination of HFF diet and Ov infection on kidney pathology via alteration of gut microbiome and proteome in hamster.