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Trichophyton mentagrophytes

ABSTRACT: Transcriptome Sequencing and Gene Expression Analysis of Trichophyton mentagrophytes under Different Culture Conditions

PROVIDER: PRJNA319476 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR3436790_1.fastq.gz	Fastqsanger.gz
	SRR3436790_2.fastq.gz	Fastqsanger.gz
	SRR3436782_1.fastq.gz	Fastqsanger.gz
	SRR3436782_2.fastq.gz	Fastqsanger.gz
	SRR3436783_1.fastq.gz	Fastqsanger.gz

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Project description:Under the action of Trichophyton 1000 UG / ml, the colony of Trichophyton mentagrophyte was completely inhibited. The spore number and germination rate of Trichophyton mentagrophyte under the action of 100ug / ml and 10ug / ml were significantly lower than those in the control group. Under the action of Trichophyton, the mitochondria in the mycelium of Trichophyton mentagrophyte were cleaved. Under the action of trichomycin, the related genes in mitochondria decreased significantly. This showed that mitochondria were obviously damaged during trichomycin treatment. It is speculated that Trichophyton can cause mitochondrial damage and reduce the efficiency of respiratory chain, but Trichophyton can synthesize enough ATP by regulating related ATP synthase to resist the invasive effect caused by Trichophyton stimulation.

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