Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Macaca mulatta

ABSTRACT: On the Relationships in Rhesus Macaques between Chronic Ethanol Consumption and the Brain Transcriptome (Central Nucleus of the Amigdala - CeA)

PROVIDER: PRJNA328925 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR3885090.fastq.gz	Fastqsanger.gz
	SRR3885100.fastq.gz	Fastqsanger.gz
	SRR3885110.fastq.gz	Fastqsanger.gz
	SRR3885091.fastq.gz	Fastqsanger.gz
	SRR3885101.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 28

Similar Datasets

Macaca mulatta

Project description:On the Relationships in Rhesus Macaques between Chronic Ethanol Consumption and the Brain Transcriptome (Cortical Area 32 - A32)

| PRJNA379499 | ENA

Macaca mulatta

Project description:Familial hypercholesterolemia of rhesus macaques

| PRJDB14155 | ENA

Macaca mulatta

Project description:HIV-1 Vaccine in Rhesus Macaques

| PRJNA593065 | ENA

Macaca mulatta

Project description:Simian Immunodeficiency Virus (SIV) infected rhesus macaques

| PRJNA765696 | ENA

Macaca mulatta

Project description:2021 H. pylori Infection in Rhesus Macaques

| PRJNA773421 | ENA

On the Relationships in Rhesus Macaques between Chronic Ethanol Consumption and the Brain Transcriptome (Central Nucleus of the Amigdala - CeA)

Project description:This is the first description of the effects of chronic ethanol consumption on the brain transcriptome in a non-human primate (rhesus macaque). Thirty male animals self-administered ethanol on a daily basis for over 12 months. Gene expression was measured with RNA-Seq in the central nucleus of the amygdala (CeA). Genes negatively correlated with consumption were enriched in functional annotations associated with translation and included clusters of ribosomal and mitochondrial ribosomal proteins. Genes positively correlated with consumption were enriched in membrane annotations including neuron and synapse part. Genes in the latter category included Ctnna2, Shank1, Vamp2, and Syn1. Gene-level expression data were clustered using the Weighted Gene Coexpression Network Analysis (WGCNA) algorithm to identify hub nodes affected by excessive consumption. Key hubs included Nf1, Nkain2, Tmem108 and Penk. The data were also analyzed for alternative exon usage (Iancu et al., 2015). Additional translation and membrane related genes affected by excessive consumption were detected. These included Grm2, Dpysl2 and Kcnc4. Overall, the data illustrate that the effects of excessive ethanol consumption are broad, consistent with the observation that ethanol affects the expression of numerous hub genes.

2017-01-13 | GSE84332 | GEO

Macaca mulatta

Project description:Transcriptomic and genomics profiling of hypertrophic cardiomyopathy in Rhesus macaques

| PRJNA1185182 | ENA

Macaca mulatta

Project description:Peripheral Blood Mononuclear Cells of Rhesus Macaques Infected with SIVmac251

| PRJNA85237 | ENA

Macaca mulatta

Project description:Leukocyte gene expression in rhesus macaques reared under different conditions

| PRJNA151869 | ENA

snRNA-seq of macaque (Macaca mulatta) adult testis

Project description:Single-nucleus RNA sequencing (snRNA-seq) was used to profile the transcriptome of 7,631 nuclei in macaque adult testis. This dataset includes two samples from two different individuals. This dataset is part of a larger evolutionary study of adult testis at the single-nucleus level (97,521 single-nuclei in total) across mammals including 10 representatives of the three main mammalian lineages: human, chimpanzee, bonobo, gorilla, gibbon, rhesus macaque, marmoset, mouse (placental mammals); grey short-tailed opossum (marsupials); and platypus (egg-laying monotremes). Corresponding data were generated for a bird (red junglefowl, the progenitor of domestic chicken), to be used as an evolutionary outgroup.

2021-11-08 | E-MTAB-11068 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data