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Caenorhabditis elegans

ABSTRACT: Comparison of RNA Pol II localization in the genomes of sig-7 (RNAi) vs WT C. elegans early stage embryos

PROVIDER: PRJNA338466 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR4017960_1.fastq.gz	Fastqsanger.gz
	SRR4017960_2.fastq.gz	Fastqsanger.gz
	SRR4017961_1.fastq.gz	Fastqsanger.gz
	SRR4017961_2.fastq.gz	Fastqsanger.gz
	SRR4017962_1.fastq.gz	Fastqsanger.gz

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Comparison of RNA Pol II localization in the genomes of sig-7 (RNAi) vs WT C. elegans early stage embryos

Project description:RNAi targeting a conserved C. elegans cyclophilin, sig-7, causes defective development and embryonic arrest consistent with a global defect in transcription. The goal of this study was to compare the location of RNA Pol II in sig-7(RNAi) embryos to the localization in L4440/RNAi control embryos to examine the global effect of loss of sig-7 on RNA Pol II regulation and its distribution within gene bodies anti-AMA-1 ChIP in 2 replicates each of sig-7(RNAi) and RNAi control early stage embryos

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