Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Candida tropicalis strain:No.1254

ABSTRACT: Candida tropicalis strain:No.1254 Transcriptome or Gene expression

PROVIDER: PRJNA341812 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR4158220_1.fastq.gz	Fastqsanger.gz
	SRR4158220_2.fastq.gz	Fastqsanger.gz
	SRR4158221_1.fastq.gz	Fastqsanger.gz
	SRR4158221_2.fastq.gz	Fastqsanger.gz
	SRR4158212_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Candida tropicalis strain:No.1254

Project description:Candida tropicalis strain:No.1254 Transcriptome or Gene expression

| PRJNA340314 | ENA

Candida tropicalis strain:No.1254

Project description:Candida tropicalis strain:No.1254 Transcriptome or Gene expression

| PRJNA371692 | ENA

Candida tropicalis

Project description:Candida tropicalis Transcriptome or Gene expression

| PRJNA842397 | ENA

Homo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)

Project description:Homo sapiens fresh whole blood was infected with Candida tropicalis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida tropicalis gene expression.

2019-07-31 | GSE114178 | GEO

Candida tropicalis strain:Z68

Project description:Candida tropicalis strain

| PRJNA903651 | ENA

Proteogenomics of Candida tropicalis – an opportunistic pathogen

Project description:Candida tropicalis is an opportunistic pathogen which causes candidiasis in immune-compromised individuals. It is one of the members of the non-albicans group of Candida that are known to be azole resistant and is frequently seen in individuals being treated for cancers, HIV-infection and bone-marrow transplant. Although the genome of C. tropicalis was sequenced in the year 2009, the genome annotation has not been supported by experimental validation. In the present study, we have carried out in-depth proteomic profiling of C. tropicalis using high-resolution Fourier transform mass spectrometry and mapped ~44% of the computationally predicted protein-coding genes with peptide level evidence. In addition to identifying 2,740 proteins in the cell lysate of this yeast, we also analysed the proteome of the conditioned media of C. tropicalis culture and identified several unique secreted proteins among a total of 780 proteins. By subjecting the mass spectrometry data derived from cell lysate and conditioned media to proteogenomic analysis, we identified 86 novel genes, 12 novel exons and corrected 49 computationally predicted gene models. To our knowledge, this is the first high-throughput proteomic study to refine the genome annotation of C. tropicalis.

2017-05-08 | PXD001071 | Pride

Candida tropicalis

Project description:Candida tropicalis X17 adapted strain RNAseq

| PRJDB12493 | ENA

Candida tropicalis strain:XR1

Project description:Candida tropicalis strain:XR1

| PRJNA728572 | ENA

Candida tropicalis

Project description:Candida tropicalis Genome sequencing

| PRJNA259321 | ENA

The gray phenotype in the human fungal pathogen Candida tropicalis

Project description:Phenotypic plasticity, the ability to switch between different morphological types, plays critical roles in environmental adaptation, leading to infections, and allowing for sexual reproduction in pathogenic Candida species. Candida tropicalis, which is both an emerging human fungal pathogen and an environmental fungus, can switch between two heritable cell types termed white and opaque. In this study, we report the discovery of a novel phenotype in C. tropicalis, named the gray phenotype. Similar to Candida albicans and Candida dubliniensis, white, gray, and opaque cell types of C. tropicalis also form a tristable switching system, where gray cells are relatively small and elongated. In C. tropicalis, gray cells exhibit intermediate levels of mating competency and virulence in a mouse systemic infection model compared to the white and opaque cell types, express a set of cell type-enriched genes, and exhibit both common and species-specific biological features. The key regulators of white-opaque transitions, Wor1 and Efg1, are not required for the gray phenotype. A comparative study of the gray phenotypes in C. tropicalis, C. albicans, and C. dubliniensis provides clues to explain the species differences in terms of virulence, ecological niches, and prevalence among these three species.

2017-01-30 | GSE81514 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data