Project description:The presence of HBeAg has been linked to an increased risk of HBV-realted HCC. However, the biological role of HBeAg in modulating host gene expression is poorly understood. Therefore, we performed a cDNA microarray in response to presence of HBeAg in Huh-7 cells. We used human primeview gene expression microarray chips to assess the host cellular mRNA expression profile in response to HBeAg in Huh7 cells
Project description:The HBeAg is a well-documented risk factor for HCC in epidemiological studies. The biological role of HBeAg in HBV-related HCC remains poorly understood. The HBeAg-mediated differential expression of host miRNAs We used miRNA microarray chips to assess the host cellular miRNA expression profile in response to HBeAg expression in Huh7 cells
Project description:CNE-2Z cells transfected with an empty vector or a TIPE1 lentiviral vector were collected for gene expression detection. Some of them, for instance, the expression of the downstream mTOR signaling pathway was dramatically upregulated. We used microarrays to detail the gene expression after transfection with TIPE1 and identified distinct classes of changed genes during this process. We used microarrays to detail the gene expression after transfected with TIPE1 and identified distinct classes of changed genes during this process.
Project description:HeLa cells transfected with an empty vector or a TIPE1 lentiviral vector were collected for gene expression detection. Some of them, for instance, the expression of genes induced by p53 was dramatically decreased. We used microarrays to detail the gene expression after transfection with TIPE1 and identified distinct classes of changed genes during this process.
Project description:Transcriptional profiling of Human Esophageal Squamous Cell Cancer Cell line (KYSE520) comparing mock transfectant (KYSE520 Mock②) with cells transfected with a mir203 expression vector (KYSE520 miR203⑥)
Project description:The expression profiling of HBV-transfected Huh-7 cells and control cells. Hepatocellular carcinoma (HCC) is one of major malignant disease worldwide, and patients with chronic hepatitis B virus (HBV) infection have a high risk of developing HCC. Via microarray gene expression analysis, we detected the gene alteration in HBV transfected hepatoma cells.