Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

16s rRNA sequence from mice commensal

ABSTRACT: Restoring dysbiotic microbiome harbored in Nlrp12-defecient mice by introducing fecal transplantation

PROVIDER: PRJNA358042 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

16s rRNA sequence from mice commensal

Project description:Nlrp12-defecient hematopoietic cells caused intestinal dysbiosis via increased proinflammatory cytokines

| PRJNA358044 | ENA

16s rRNA sequence from mice commensal

Project description:16s rRNA sequencing of fecal DNA from wild type and Nlrp12-deficient mice

| PRJNA358041 | ENA

Nlrp12 expressing heamatopoitic cells maintain the intestinal microbiome symbiosis.

Project description:Nlrp12-/- mice host a dysbiotic microbiome. After performing bone marrow transplantation study, we found mice receiving Nlrp12-/- haematopoitic cells pheno-copied the dysbiotic microbiome in the Nlrp12-/- mice.

| PRJEB18700 | ENA

16S rRNA metagenome

Project description:Faecal Microbiota Transplantation on DSS-Induced Ulcerative Colitis in a Pseudo Germ-Free Mouse

| PRJNA1016130 | ENA

Genotyping of commensal Neisseria spp strains by pulsed-field gel electrophoresis and 16S rRNA gene sequencing.

Project description:BackgroundWe investigated the diversity of the primary sequences of the 16S rRNA genes among 46 commensal Neisseria strains and evaluated the use of this approach as a molecular typing tool in comparison with PFGE analysis.MethodsIdentification to the genus was done using conventional methods and API NH (bio-Mérieux® ). Identification to species level was based on 16S rRNA gene sequencing. PFGE analysis was done using SpeI.ResultsFourteen, two, three and fourteen 16S rRNA sequence types were found among twenty Neisseria flavescens, two Neisseria sicca, five Neisseria macacae and nineteen Neisseria mucosa clinical isolates. Forty-three different PFGE patterns were found among the tested strains.ConclusionWe demonstrated a high diversity among 16S rRNA genes which was reflected by PFGE analysis.

| S-EPMC6817022 | biostudies-literature

Identifying the dominant soil bacterial taxa in libraries of 16S rRNA and 16S rRNA genes.

Project description: Not available

| S-EPMC1393246 | biostudies-literature

The Nlrp12 inflammasome negatively regulates NOD2-mediated adjuvanticity, endotoxic shock and host defence afforded by an immunomodulatory muropeptide.

Project description:Transcriptional profiling of intestinal response to Citrobacter rodentium in wild-type and Nlrp12-deficient mice Four-conditions experiment, Nlrp12-deficient mouse infected by Citrobacter rodentium at day 7 versus non-infected Nlrp12-deficient mice with two biologicals replicates , Wild-type mouse infected by Citrobacter rodentium at day 7 versus non-infected Wild-type mice with two biologicals replicates and Nlrp12-deficient mouse infected by Citrobacter rodentium versus Control mouse infected by Citrobacter rodentium at 2 differents times ( day 0 and post infection at day 7 ) with three biologicals replicates

2015-07-25 | E-GEOD-59940 | biostudies-arrayexpress

RNAseq analysis of gene expression in colorectal tumors of wild-type and Nlrp12-/- mice

Project description:Background: NLRP12 is a cytosolic pattern recognition receptor in the family of NOD-like receptor. NLRP12 has been shown to suppress colorectal tumorigenesis. However, the precise mechansim of NLRP12-mediated regualtion of colorectal cancer is unknown. Results: RNAseq data demonstrate higher expression of oncogenes, matrix degrading enzymes such as matrix metaloproteinases (MMPs), and genes involved in tumor invasion in Nlrp12-/- compared to wild-type tumors. Notably, several of the genes highly induced in Nlrp12-/- tumors are regulated by the Wnt/b-catenin pathway. Conclusion: NLRP12 negatively regualtes the Wnt/b-catenin pathway to suppress colorectal cancer progression and invasion.

2020-10-01 | GSE149769 | GEO

Gut Microbiota Orchestrates Energy Homeostasis during Cold [16S rRNA gene V4-region miSeq]

Project description:Microbial functions in the host physiology are a result of co-evolution between microbial communities and their hosts. Here we show that cold exposure leads to marked shift of the microbiota composition, referred to as cold microbiota. Transplantation of the cold microbiota to germ-free mice is sufficient to increase the insulin sensitivity of the host, and enable complete tolerance to cold partly by promoting the white fat browning, leading to increased energy expenditure and fat loss. During prolonged cold however, the body weight loss is attenuated, caused by adaptive mechanisms maximising caloric uptake and increasing intestinal, villi and microvilli lengths. This increased absorptive surface is promoted by the cold microbiota - effect that can be diminished by co-transplanting the most downregulated bacterial strain from the Verrucomicrobia phylum, Akkermansia muciniphila, during the cold microbiota transfer. Our results demonstrate the microbiota as a key factor orchestrating the overall energy homeostasis during increased demand.

2015-12-03 | GSE74227 | GEO

RmtC 16S rRNA methyltransferase in Australia.

Project description: Not available

| S-EPMC2224735 | biostudies-literature