Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Macaca fascicularis

ABSTRACT: Diverse Non-Genetic Allele Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain [Primate Parents]

PROVIDER: PRJNA362512 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5184390.fastq.gz	Fastqsanger.gz
	SRR5184390_1.fastq.gz	Fastqsanger.gz
	SRR5184390_2.fastq.gz	Fastqsanger.gz
	SRR5184391.fastq.gz	Fastqsanger.gz
	SRR5184391_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 45

Similar Datasets

Macaca fascicularis

Project description:Diverse Non-Genetic Allele Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain [Primate Daughters]

| PRJNA362511 | ENA

scRNA-seq of adult Macaca fascicularis brain

Project description:With improved whole-cell isolation protocols, we performed single-cell RNA sequencing (scRNA-seq) and profiled the transcriptomes from adult non-human primate brain. We identified discriminative cell populations with canonical and novel markers. Cross-species projection demonstrated the evolutionary conservation among mouse, monkey, and human. This dataset serves as a detailed transcriptomic atlas for understanding the adult primate central nervous system.

2022-05-07 | E-MTAB-10225 | biostudies-arrayexpress

Diverse Non-Genetic Allele Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain

Project description:Diverse Non-Genetic Allele Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain

| PRJNA362348 | ENA

Mus musculus

Project description:Diverse Non-Genetic Allele Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain [HybridMouseDRN]

| PRJNA362510 | ENA

Macaca fascicularis

Project description:Non-human primate Raw sequence reads

| PRJNA505071 | ENA

Macaca fascicularis

Project description:Synthetic primate embryos model gastrulation and early pregnancy

| PRJNA1058618 | ENA

Gene expression dataset for whole cochlea of Macaca fascicularis

Project description:Macaca fascicularis (long-tailed, cynomolgus, or crab-eating macaque) is a highly advantageous model in which to study human cochlea with regard to both evolutionary proximity and physiological similarity of the auditory system. To better understand the properties of primate cochlear function, we analyzed the genes predominantly expressed in M. fascicularis cochlea.

2018-10-14 | GSE111693 | GEO

Expression profiling in Macaca fascicularis liver samples

Project description:The long-tailed macaque, also referred to as cynomolgus monkey (Macaca fascicularis), is one of the most important non-human primate animal models in basic and applied biomedical research. To improve the predictive power of primate experiments for humans, we determined the genome sequence of a Macaca fascicularis female of Mauritian origin using a whole-genome shotgun sequencing approach. We applied a template switch strategy which employs either the rhesus or the human genome to assemble sequence reads. The 6-fold sequence coverage of the draft genome sequence enabled discovery of about 2.1 million potential single-nucleotide polymorphisms based on occurrence of a dimorphic nucleotide at a given position in the genome sequence. Homology-based annotation allowed us to identify 17,387 orthologs of human protein-coding genes in the M. fascicularis draft genome and the predicted transcripts enabled the design of a M. fascicularis-specific gene expression microarray. Using liver samples from 36 individuals of different geographic origin, we identified 718 genes with highly variable expression in liver, whereas the majority of the transcriptome shows relatively stable and comparable expression. Knowledge of the M. fascicularis draft genome is an important contribution to both the use of this animal in disease models and the safety assessment of drugs and their metabolites. In particular, this information allows high-resolution genotyping and microarray-based gene expression profiling for animal stratification, thereby allowing the use of well-characterized animals for safety testing. Finally, the genome sequence presented here is a significant contribution to the global "3R" animal welfare initiative, which has the goal to reduce, refine and replace animal experiments.

2011-08-25 | GSE30184 | GEO

Macaca fascicularis

Project description:Transcriptomics analysis of five tissues in a non-human primate model of depression

| PRJNA737620 | ENA

Macaca fascicularis

Project description:WFUBMC Primate Center X-96-23: Cynomolgus macaque response to hormone replacement therapy

| PRJNA137499 | ENA