Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Variation in DNA methylation is not consistently reflected by sociality in Hymenoptera

ABSTRACT: Variation in DNA methylation is not consistently reflected by sociality in Hymenoptera

PROVIDER: PRJNA362731 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5192885_1.fastq.gz	Fastqsanger.gz
	SRR5192885_2.fastq.gz	Fastqsanger.gz
	SRR5192886_1.fastq.gz	Fastqsanger.gz
	SRR5192886_2.fastq.gz	Fastqsanger.gz
	SRR5192887_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Variation in DNA methylation is not consistently reflected by sociality in Hymenoptera

Project description:We used pooled samples of adult females from 3 species of Hymenoptera to generate single-base resolution DNA methylation maps.

2017-07-14 | GSE93893 | GEO

Variation in DNA Methylation Is Not Consistently Reflected by Sociality in Hymenoptera.

Project description:Changes in gene regulation that underlie phenotypic evolution can be encoded directly in the DNA sequence or mediated by chromatin modifications such as DNA methylation. It has been hypothesized that the evolution of eusocial division of labor is associated with enhanced gene regulatory potential, which may include expansions in DNA methylation in the genomes of Hymenoptera (bees, ants, wasps, and sawflies). Recently, this hypothesis garnered support from analyses of a commonly used metric to estimate DNA methylation in silico, CpG content. Here, we test this hypothesis using direct, nucleotide-level measures of DNA methylation across nine species of Hymenoptera. In doing so, we generated new DNA methylomes for three species of interest, including one solitary and one facultatively eusocial halictid bee and a sawfly. We demonstrate that the strength of correlation between CpG content and DNA methylation varies widely among hymenopteran taxa, highlighting shortcomings in the utility of CpG content as a proxy for DNA methylation in comparative studies of taxa with sparse DNA methylomes. We observed strikingly high levels of DNA methylation in the sawfly relative to other investigated hymenopterans. Analyses of molecular evolution suggest the relatively distinct sawfly DNA methylome may be associated with positive selection on functional DNMT3 domains. Sawflies are an outgroup to all ants, bees, and wasps, and no sawfly species are eusocial. We find no evidence that either global expansions or variation within individual ortholog groups in DNA methylation are consistently associated with the evolution of social behavior.

| S-EPMC5522706 | biostudies-literature

Hymenoptera

Project description:Hymenoptera Genome sequencing and assembly

| PRJNA542636 | ENA

Hymenoptera

Project description:Key innovations and the diversification of Hymenoptera

| PRJNA811764 | ENA

Hymenoptera

Project description:Diverse Hymenoptera associated with rose galls (bedeguar) - marker gene amplicon sequencing reads

| PRJNA1019940 | ENA

Trisomy 21 consistently activates the interferon response

Project description:Trisomy 21 consistently activates the interferon response

| PRJNA317169 | ENA

Hymenoptera sp. 4 GYN-2021

Project description:Hymenoptera sp. 4 GYN-2021 overview

| PRJNA890369 | ENA

Mutillidae (Hymenoptera)

Project description:A phylogenomic perspective on the Systematics of Mutillidae (Hymenoptera), with emphasis on Sphaeropthalminae (genome sequencing and assembly)

| PRJNA664086 | ENA

Genome-wide analysis of transcript isoform variation in humans

Project description:We have performed a genome-wide analysis of common genetic variation controlling differential expression of transcript isoforms in the CEU HapMap population using a comprehensive exon tiling microarray covering 17,897 genes. We detected 324 genes with significant associations between flanking SNPs and transcript levels. Of these, 39% reflected changes in whole gene expression and 55% reflected transcript isoform changes such as splicing variants (exon skipping, alternate splice site usage, intron retention), differential 5’ UTR (initiation of transcription) usage, and differential 3’ UTR (alternative polyadenylation) usage. These results demonstrate that the regulatory effects of genetic variation in a normal human population are drastically more complex than previously observed. This additional layer of molecular diversity may account for natural phenotypic variation and disease susceptibility. Keywords: Comparative genomic hybridiation within the CEU HapMap population

2008-01-13 | GSE9372 | GEO

Hymenoptera: Aculeata

Project description:Enriching the ant tree of life: enhanced UCE bait set for genome-scale phylogenetics of ants and other Hymenoptera

| PRJNA360290 | ENA