Project description:This metabolomics study evaluated kidney tissue from wild-type and meprin β knockout mice after induction of diabetes with streptozotocin or treatment with sodium citrate control to understand how these factors influence the metabotype.
Project description:Gene Set Enrichment Analysis of PEDF knockout livers revealed induction of pathways associated with experimental and human HCC and a transcriptional profile characterized by Wnt/β-catenin activation Genome-wide expression analysis of liver tissue of wild type vs PEDF knockout animals fed high fat diet
Project description:To gain insight into the potential molecular mechanisms by which PGRN regulates influenza viral replication, proteomic analyses of whole mouse lung tissue from wild-type (WT) versus (vs) PGRN knockout (KO) mice were performed to identify proteins regulated by the absence vs presence of PGRN.
