Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Insect gut metagenome

ABSTRACT: Thaumetopoea pityocampa gut bacterial community

PROVIDER: PRJNA379119 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5349200.fastq.gz	Fastqsanger.gz
	SRR5349210.fastq.gz	Fastqsanger.gz
	SRR5349220.fastq.gz	Fastqsanger.gz
	SRR5349280.fastq.gz	Fastqsanger.gz
	SRR5349430.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 45

Similar Datasets

Thaumetopoea pityocampa

Project description:Thaumetopoea pityocampa overview

| PRJNA268393 | ENA

Thaumetopoea pityocampa strain:pine forest named Mata Nacional de Leiria (Portugal)

Project description:Thaumetopoea pityocampa Transcriptome

| PRJNA232643 | ENA

insect gut metagenome

Project description:Bacterial Community of the Spined Soldier Bug Gut

| PRJNA391927 | ENA

insect gut metagenome

Project description:Gut Bacterial Community of the Xylophagous Cockroaches Metagenome

| PRJNA284583 | ENA

insect gut metagenome

Project description:Metagenomic analyses on the bacterial gut community of the glacier stonefly

| PRJDB7204 | ENA

insect gut metagenome

Project description:Analysis of bacterial community in the gut of Trypoxylus dichotoma larva

| PRJDB9244 | ENA

Integrated microbiome and host profiling in a mouse model of colitis suggests host immune activity drives changes in the gut micro-environment that influence both microbial community structure and gene expression

Project description:The gut microbiome is significantly altered in inflammatory bowel diseases, but the basis of these changes is not well understood. We have combined metagenomic and metatranscriptomic profiling of the gut microbiome to assess changes to both bacterial community structure and transcriptional activity in a mouse model of colitis. Gene families involved in microbial resistance to oxidative stress, including Dps/ferritin, Fe-dependent peroxidase and glutathione S-transferase, were transcriptionally up-regulated in colitis, implicating a role for increased oxygen tension in gut microbiota modulation. Transcriptional profiling of the host gut tissue and host RNA in the gut lumen revealed a marked increase in the transcription of genes with an activated macrophage and granulocyte signature, suggesting the involvement of these cell types in influencing microbial gene expression. Down-regulation of host glycosylation genes further supports a role for inflammation-driven changes to the gut niche that may impact the microbiome. We propose that members of the bacterial community react to inflammation-associated increased oxygen tension by inducing genes involved in oxidative stress resistance. Furthermore, correlated transcriptional responses between host glycosylation and bacterial glycan utilisation support a role for altered usage of host-derived carbohydrates in colitis. Complementary transcription profiling data from the mouse hosts have also been deposited at ArrayExpress under accession number E-MTAB-3590 ( http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-3590/ ).

2015-05-22 | E-MTAB-3562 | biostudies-arrayexpress

Thaumetopoea pityocampa

Project description:Thaumetopoea pityocampa Raw sequence reads

| PRJNA662036 | ENA

Morphine treatment induces distinct changes in the gut microbiome at day 3 post treatment

Project description:Opioids such as morphine have many beneficial properties as analgesics, however, opioids may induce multiple adverse gastrointestinal symptoms. We have recently demonstrated that morphine treatment results in significant disruption in gut barrier function leading to increased translocation of gut commensal bacteria. However, it is unclear how opioids modulate the gut homeostasis. By using a mouse model of morphine treatment, we studied effects of morphine treatment on gut microbiome. We characterized phylogenetic profiles of gut microbes, and found a significant shift in the gut microbiome and increase of pathogenic bacteria following morphine treatment when compared to placebo. In the present study, wild type mice (C57BL/6J) were implanted with placebo, morphine pellets subcutaneously. Fecal matter were taken for bacterial 16s rDNA sequencing analysis at day 3 post treatment. A scatter plot based on an unweighted UniFrac distance matrics obtained from the sequences at OTU level with 97% similarity showed a distinct clustering of the community composition between the morphine and placebo treated groups. By using the chao1 index to evaluate alpha diversity (that is diversity within a group) and using unweighted UniFrac distance to evaluate beta diversity (that is diversity between groups, comparing microbial community based on compositional structures), we found that morphine treatment results in a significant decrease in alpha diversity and shift in fecal microbiome at day 3 post treatment compared to placebo treatment. Taxonomical analysis showed that morphine treatment results in a significant increase of potential pathogenic bacteria. Our study shed light on effects of morphine on the gut microbiome, and its role in the gut homeostasis.

2018-04-16 | E-MTAB-5546 | biostudies-arrayexpress

insect gut metagenome

Project description:insect gut bacterial symbionts Targeted loci

| PRJNA348558 | ENA