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HPIP controls osteoarthritis cartilage degeneration

ABSTRACT: HPIP controls osteoarthritis cartilage degeneration

PROVIDER: PRJNA391300 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5725510_1.fastq.gz	Fastqsanger.gz
	SRR5725510_2.fastq.gz	Fastqsanger.gz
	SRR5725511_1.fastq.gz	Fastqsanger.gz
	SRR5725511_2.fastq.gz	Fastqsanger.gz
	SRR5725512_1.fastq.gz	Fastqsanger.gz

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Project description:To underly the potential downstream transcriptional regulation of HPIP that could account for cartilage and skeletal development. RNA-seq analysis were performed in HPIP knockout and control primary chondrocytes.Among the 1271 significantly differentially expressed genes, transcripts for 486 (7%) of them were upregulated while transcripts for 785 (11%) were downregulated in HPIP knockout chondrocytes compared to the controls. We found HPIP was closely correlated with the cartilage development.

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