HPIP controls osteoarthritis cartilage degeneration [RNA-seq]
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ABSTRACT: To underly the potential downstream transcriptional regulation of HPIP that could account for cartilage and skeletal development. RNA-seq analysis were performed in HPIP knockout and control primary chondrocytes.Among the 1271 significantly differentially expressed genes, transcripts for 486 (7%) of them were upregulated while transcripts for 785 (11%) were downregulated in HPIP knockout chondrocytes compared to the controls. We found HPIP was closely correlated with the cartilage development.
ORGANISM(S): Homo sapiens
PROVIDER: GSE100268 | GEO | 2017/06/23
SECONDARY ACCESSION(S): PRJNA391184
REPOSITORIES: GEO
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