Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mbd3-null and control lymphoid progenitor cells

ABSTRACT: Mbd3-null and control lymphoid progenitor cells

PROVIDER: PRJNA395314 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5854390.fastq.gz	Fastqsanger.gz
	SRR5854400.fastq.gz	Fastqsanger.gz
	SRR5854410.fastq.gz	Fastqsanger.gz
	SRR5854420.fastq.gz	Fastqsanger.gz
	SRR5854430.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 798

Similar Datasets

Single cell RNA-sequencing of Mbd3-null and control lymphoid progenitor cells

Project description:To determine the role of Mbd3/NuRD in lymphopoiesis, gene expression in single Mbd3-deleted and control lymphoid progenitor cells was analysed using single cell RNA-seq

2017-09-08 | GSE101712 | GEO

RNA-sequencing of Mbd3-null and control haematopoietic stem cell and lymphoid progenitor cell populations

Project description:To determine the role of Mbd3/NuRD in lymphopoiesis, gene expression in purified populations of Mbd3-deleted and control lymphoid progenitor cells was analysed using RNA-seq.

2017-07-22 | GSE101732 | GEO

ATAC-seq analysis of chromatin accessibility in Mbd3-null and control lymphoid progenitor cells

Project description:To determine the role of Mbd3/NuRD in lymphopoiesis, chromatin accessbility was analysed in purified populations of Mbd3-deleted and control lymphoid progenitor cells using the assay for transposase-accessible chromatin using sequencing (ATAC-seq).

2017-07-22 | GSE101729 | GEO

Mbd3-null and control lymphoid progenitor cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2017-07-22 | GSE101735 | GEO

Mus musculus

Project description:Single cell RNA-sequencing of Mbd3-null and control lymphoid progenitor cells

| PRJNA395242 | ENA

Mus musculus

Project description:ATAC-seq analysis of chromatin accessibility in Mbd3-null and control lymphoid progenitor cells

| PRJNA395309 | ENA

Mus musculus

Project description:RNA-sequencing of Mbd3-null and control haematopoietic stem cell and lymphoid progenitor cell populations

| PRJNA395315 | ENA

scRNA-seq of index-sorted myeloid and lymphoid progenitor cells and differentiated pDCs

Project description:Nine different cell types (common dendritic progenitor (CDP), pre-conventional dendritic cell (pre-cDC), common dendritic progenitor (CDPr, according to Rodrigues et al., but this population was flawed in sorting purity), Flt3+ CD11c+ Siglec-H+ CCR9-low B220-low progenitor cell (lo-lo), Flt3 + CD11c+ Siglec-H+ CCR9-low B220-high progenitor cell (lo-hi), plasmacytoid dendritic cell (pDC), Ly6D+ lymphoid progenitor (SP), Ly6D+ Siglec-H+ lymphoid progenitor (DP) and common lymphoid progenitor (CLP)) were sorted to allow for analysis of their transcriptomic relation and/or similarity. The pDC_precursor_scvelo.h5ad file is a processed file ready for direct downstream analysis with scvelo.

2022-05-21 | E-MTAB-11752 | biostudies-arrayexpress

Early innate lymphoid cell progenitor

Project description:We identified a new type of bone marrow progenitors termed early innate lymphoid cell progenitor (EILP) using TCF-1 GFP reporter mice. We compared the transcriptomes of early innate lymphoid cell progenitors (EILP) with other early progenitors, including HSC, LMPP, CMP, CLP, ETP and DN3.

2015-08-17 | GSE69789 | GEO

MBD3 localization by ChIP-seq

Project description:Maintenance of chromatin structure is essential to eukaryotic life; dysregulation is known to be causal for aberrant development and disease. The Mi-2/nucleosome remodeling and histone deacetylase (NuRD) complex is a multiprotein machine proposed to regulate chromatin structure by nucleosome remodeling and histone deacetylation activities. We identified the localization of MBD3, a component of Mi-2/NuRD complex, in two breast cancer cell lines (MCF7 and MDA-MB-231) using ChIP-Seq. MBD3 showed cell-type specific localization with overlap across cell lines being less than 50%. MBD3 localized across gene bodies, peaking around the transcription start site (TSS). Contrary to existing models, MBD3 preferentially associated with CpG rich promoters marked by H3K4me3. These data suggest that MBD3, and by extension the Mi-2/NuRD complex, may have roles in fine tuning expression for active genes. These data represent an important first step in defining regulatory mechanisms by which Mi-2/NuRD complex controls chromatin structure and gene expression. Identification of MBD3 localization in human breast cancer cell lines

2013-10-31 | E-GEOD-44737 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data