Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: Transcriptomic analysis of senescent cells upon EXOC7 knockdown.

PROVIDER: PRJNA395378 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5859300.fastq.gz	Fastqsanger.gz
	SRR5859301.fastq.gz	Fastqsanger.gz
	SRR5859302.fastq.gz	Fastqsanger.gz
	SRR5859303.fastq.gz	Fastqsanger.gz
	SRR5859294.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 15

Similar Datasets

Homo sapiens

Project description:Transcriptomic analysis of senescent cells upon PTBP1 knockdown.

| PRJNA395363 | ENA

Homo sapiens

Project description:Transcriptomic analysis of senescent cells upon knockdown of 38 candidate SASP-specific regulators.

| PRJNA395386 | ENA

Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown

Project description:Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown

| PRJNA395374 | ENA

Homo sapiens

Project description:Expression analysis upon NAMPT knockdown in MCF-7 cells

| PRJNA113977 | ENA

Homo sapiens

Project description:Expression analysis upon NMNAT1 knockdown in MCF-7 cells

| PRJNA113979 | ENA

Homo sapiens

Project description:Expression analysis upon SIRT1 knockdown in MCF-7 cells

| PRJNA113981 | ENA

Homo sapiens

Project description:Transcriptomic analysis of YAP1 knockdown glioblastoma cells

| PRJNA279792 | ENA

Homo sapiens foetal mesenchymal stem cell miRNA transcriptome

Project description:We have sequenced miRNA libraries from human embryonic, neural and foetal mesenchymal stem cells. We report that the majority of miRNA genes encode mature isomers that vary in size by one or more bases at the 3’ and/or 5’ end of the miRNA. Northern blotting for individual miRNAs showed that the proportions of isomiRs expressed by a single miRNA gene often differ between cell and tissue types. IsomiRs were readily co-immunoprecipitated with Argonaute proteins in vivo and were active in luciferase assays, indicating that they are functional. Bioinformatics analysis predicts substantial differences in targeting between miRNAs with minor 5’ differences and in support of this we report that a 5’ isomiR-9-1 gained the ability to inhibit the expression of DNMT3B and NCAM2 but lost the ability to inhibit CDH1 in vitro. This result was confirmed by the use of isomiR-specific sponges. Our analysis of the miRGator database indicates that a small percentage of human miRNA genes express isomiRs as the dominant transcript in certain cell types and analysis of miRBase shows that 5’ isomiRs have replaced canonical miRNAs many times during evolution. This strongly indicates that isomiRs are of functional importance and have contributed to the evolution of miRNA genes

2014-08-06 | GSE58734 | GEO

Homo sapiens

Project description:Gene expression analysis upon UGT1A_i2 knockdown

| PRJNA208949 | ENA

Homo sapiens immortalized MSCs: 3A6

Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.

2010-09-25 | GSE24338 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data