Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-61130

ABSTRACT: Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant

OTHER RELATED OMICS DATASETS IN: PRJNA260300

PROVIDER: E-GEOD-61130 | ExpressionAtlas | 2025-01-24

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-61130-analysis-methods.tsv	Tabular
	E-GEOD-61130-analytics.tsv	Tabular
	E-GEOD-61130-analytics.tsv.undecorated	Tabular
	E-GEOD-61130-analytics.tsv.undecorated.unrounded	Tabular
	E-GEOD-61130-analytics.tsv.unrounded	Tabular

Items per page:

1 - 5 of 105

Similar Datasets

Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant

Project description:We expressed either a wt or a phosphomutant version of ZFP36L1 in IMR90 ER:RAS cells. 7 days upon RAS induction (when the cells reach a fully senescent phenotype) we collected the RNA. ZFP36L1 is a RNA binding protein that binds to AU-rich elements in the 3âUTR of mRNAs and triggers their degradation. Our previous experiments showed that the activity of ZFP36L1 was key in the regulation of the senescent phenotype.By performing RNAseq we have uncovered the effect of expressing a constitutively active mutant of ZFP36L1 within the senescent transcriptome. 4 samples examined: Non-senescent cells (EV - 4OHT), Senescent cells (EV + 4OHT), Senescent cells expressing ZFP36L1wt and Senescent cells expressing ZFP36L1mut

2015-07-07 | E-GEOD-61130 | biostudies-arrayexpress

Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant

Project description:We expressed either a wt or a phosphomutant version of ZFP36L1 in IMR90 ER:RAS cells. 7 days upon RAS induction (when the cells reach a fully senescent phenotype) we collected the RNA. ZFP36L1 is a RNA binding protein that binds to AU-rich elements in the 3’UTR of mRNAs and triggers their degradation. Our previous experiments showed that the activity of ZFP36L1 was key in the regulation of the senescent phenotype.By performing RNAseq we have uncovered the effect of expressing a constitutively active mutant of ZFP36L1 within the senescent transcriptome.

2015-07-07 | GSE61130 | GEO

Homo sapiens

Project description:Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant

| PRJNA260300 | ENA

E-GEOD-54357

Project description:Transcriptome analysis in rice smos1 mutant

2016-01-04 | E-GEOD-54357 | ExpressionAtlas

E-GEOD-37031

Project description:Transcriptome Analysis from non-alcoholic steatohepatitis (NASH)

2025-01-24 | E-GEOD-37031 | ExpressionAtlas

E-GEOD-51215

Project description:Transcriptome analysis in flavonoid overaccumulating and lacking Arabidopsis.

2015-05-11 | E-GEOD-51215 | ExpressionAtlas

E-GEOD-66666

Project description:Transcriptome-wide analysis of gene expression in 4-day-old WT and athb1-1 mutant seedlings grown under short day conditions

2019-05-14 | E-GEOD-66666 | ExpressionAtlas

E-GEOD-39733

Project description:Microarray analysis of gene expression changes in human A549 lung cancer cells upon siRNA knockdown of FAM60A and SDS3

2025-01-24 | E-GEOD-39733 | ExpressionAtlas

E-GEOD-100667

Project description:Transcriptome analysis of Htn1 mediated resistance against E .turcium

2020-04-17 | E-GEOD-100667 | ExpressionAtlas

E-GEOD-35642

Project description:Transcriptome analysis of a chronic in vitro model of Parkinsonism

2025-01-24 | E-GEOD-35642 | ExpressionAtlas

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data