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Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA)

ABSTRACT: Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA)

OTHER RELATED OMICS DATASETS IN: GSE104666

PROVIDER: PRJNA413424 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6133860_1.fastq.gz	Fastqsanger.gz
	SRR6133860_2.fastq.gz	Fastqsanger.gz
	SRR6133861_1.fastq.gz	Fastqsanger.gz
	SRR6133861_2.fastq.gz	Fastqsanger.gz
	SRR6133862_1.fastq.gz	Fastqsanger.gz

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Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA)

Project description:The aim of the project was to characterize the transcriptional landscape of human HUVEC cells exposed to oxidative stress (oxstress). In order to do so cell cultures have been exposed to 200uM H2O2 for either 16 hours or 36 hours to induce oxstress. Total ribodepleted RNA obtained from both time points have been sequenced and small RNA for the 16 hours time point have been sequenced as well. Datasets have been characterized and overlapped. This entry contains the dataset of total ribodepleted RNA.

2018-02-22 | GSE104664 | GEO

Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Small RNA)

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Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress

Project description:Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress

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Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Small RNA)

Project description:Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Small RNA)

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Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-02-22 | GSE104666 | GEO

Regulation of oxidative stress in endothelial cells exposed to high glucose by selected microRNA

Project description:Hyperglycemia is the hallmark of diabetes mellitus that results in oxidative stress, endothelial dysfunction and vascular complications of diabetes. MicroRNAs (miRNAs) play a role in the development of endothelial dysfunction in diabetes, with potential application for the future therapy of diabetic vascular complications. However, there is a limited number of studies that characterize the miRNA profile of endothelial cells exposed to hyperglycemic condition. This study aimed to identify the miRNA profile of human umbilical vein endothelial cells (HUVEC) exposed to hyperglycemic state using RNA sequencing analysis.

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Comparative transcriptomic profiling of unstimulated and inflamed HUVEC exposed to apple procyanidin oligomers

Project description:We used microarrays to investigate changes in gene expression of human vascular endothelial cells (HUVEC) exposed to an apple extract enriched in procyanidins of low-medium molecular weight (dp3.9) to determine possible protective effects induced by these plant derived compounds on the endothelial cells. Keywords: Comparative gene expression, Control vs Treated cells (response to exposure with xenobiotics plant polyphenols)

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Project description:To understand the molecular mechanism underlying inflammatory reaction in vascular system post exposure to ionizing radiation, we carried out microarray analysis in HUVEC exposed with X-ray HUVEC were irradiated with X-ray (2.5 Gy) and then cultured for 6, 12, and 24 hr. Total RNA were extracted from the tissue by QIAGEN Rneasy mini kit.

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